Results 41 to 50 of about 2,070,998 (294)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

State-related electroencephalographic deviances in attention deficit hyperactivity disorder [PDF]

, 2006
The dynamic security region (DSR) of bulk power system has been accepted more and more in recent years for providing plenty of security information and good prospect in online application.
Inez Buyck, Jan R. Wiersema, Achenbach, American Psychiatric Association, Antrop, Arns, Barry, Barry, Barry, Barry, Barry, Biederman, Boord, Börger, Buyck, Chabot, Clarke, Clarke, Clarke, Clarke, Clarke, Clarke, Clarke, Clarke, Clarke, Clarke, Cohen, Connor, Coolidge, Critchley, Dupuy, Dupuy, Fein, Fonseca, Gasser, González-Castro, Gratton, Grégoire, Hale, Hale, Hale, Hüfner, Karhu, Keune, Konrad, Lansbergen, Liechti, Loo, Loo, Loo, Loo, Metin, Monastra, Nazari, Ogrim, Oostenveld, Pelham, Ristanovic, Samson-Dollfus, Sanders, Schaffer, Sergeant, Shi, Snyder, Sonuga-Barke, Sonuga-Barke, Swartwood, van der Meere, van Dongen-Boomsma, Wechsler, Wiersema, Willcutt, Woltering, World Health Organization, Zentall   +74 more
core   +3 more sources

Enhancing Physical Layer Security in AF Relay Assisted Multi-Carrier Wireless Transmission

, 2018
In this paper, we study the physical layer security (PLS) problem in the dual hop orthogonal frequency division multiplexing (OFDM) based wireless communication system.
Ali, Zain, Aman, Waqas, Furqan, Haji M., Sidhu, Guftaar Ahmad Sardar   +3 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Coordinated Low-Carbon Optimal Dispatching on Source-Demand Side for Integrated Electricity-Gas System

CSEE Journal of Power and Energy Systems
With the advancement of the “carbon peaking” and “carbon neutrality” objectives, concerns regarding carbon emissions in energy system dispatching have attracted much attention.
Chunyan Li, Zhichao Yan, Yiming Yao, Zhanwen Tang, Changzheng Shao   +4 more
doaj   +1 more source

AC Surface Flashover and Gas Generation Difference of the Cellulose Insulation Pressboard Immersed in Novel 3-Element Mixed Oil and Mineral Oil

IEEE Access, 2019
Surface flashover fault is one of the most challenge issues in oil-cellulose insulation pressboard system used in power transformer. In this study, a comparative study of the AC surface flashover properties of the novel 3-element mixed oil-cellulose ...
Xin Chen, Jian Hao, Ruijin Liao, Jian Li, Lijun Yang, Dawei Feng   +5 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A selection principle of submodule switching state vectors for switching frequency reduction in voltage self‐balancing half‐bridge modular multilevel converters

IET Power Electronics
The problem of submodule switching frequency reduction in half‐bridge modular multilevel converters (HB‐MMCs) with capacitor voltage self‐balancing control is considered and explored in this paper.
Yiyuan Zhou, Liang Qin, Shiqi Yang, Qing Wang, Kaipei Liu   +4 more
doaj   +1 more source

Research on Discharging Current Distribution of Grounding Electrodes

IEEE Access, 2019
Grounding electrodes with good current discharging performance can ensure the reliability of power system security. Discharging current is not only the reason for accelerating the corrosion, but also the key indicator of the grounding electrodes ...
Zhanlong Zhang, Yihua Dan, Jing Zou, Guohua Liu, Chengfeng Gao, Yiqiao Li   +5 more
doaj   +1 more source