Results 81 to 90 of about 526,265 (313)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Small signal stability analysis of power systems with high penetration of wind power [PDF]

, 2013
The integration of large amount of wind power into a power system imposes a new challenge for the secure and economic operation of the system. It is necessary to investigate the impacts of wind power generation on the dynamic behavior of the power system
Ledwich, Gerard, He, Ping, Wen, Fushuan, Xue, Yusheng   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Koopman model predictive control based load modulation for primary frequency regulation

IET Generation, Transmission & Distribution
Conventional power systems function under the assumption that loads are uncontrollable, and that the generation control is the primary means of preserving system voltage, frequency, and stability.
Ahmed Husham, Innocent Kamwa, Hussein Suprême   +2 more
doaj   +1 more source

Power system stabilizer control for wind power to enhance power system stability

, 2011
The paper presents a small signal stability analysis for power systems with wind farm interaction. Power systems have damping oscillation modes that can be excited by disturbance or fault in the grid. The power converters of the wind farms can be used to reduce these oscillations and make the system more stable.
Domínguez García, José Luís, Gomis Bellmunt, Oriol, Bianchi, Fernando Daniel, Sumper, Andreas   +3 more
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

IMPROVING DYNAMIC STABILITY OF POWER SYSTEMS BY USING AVR, POWER SYSTEM STABILIZER

INTERNATIONAL JOURNAL OF ELECTRICAL ENGINEERING & TECHNOLOGY , 2019
This paper introduced a sum method for controlling electrical power systems for multi-machines under dynamic loads by using artificial intelligence. This paper includes complete descriptions of the sum methods used to controlling dynamic power system stability through the method of recognizing pattern and proposition of suitable control systems for re ...
EL-SAIED OTHMAN, MOHAMED I. EL-SAYED, FUHAID BASHEER   +2 more
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Impact of power system stabilizer installation on steady state stability performance

, 1990
The fast expansion of both transmission network and generation in the fast developing power system necessitates a continuous updating for its stability performance.
Elrazaz, Z., Z. Elrazaz, Abdulaziz A. El-Sulaiman, El-Sulaiman, Abdulaziz A., Barakat, M., M. Barakat   +5 more
core   +1 more source