Results 91 to 100 of about 311,115 (293)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2019 Offshore power generation has emerged as a prominent source of energy and the installed capacity of new plants has been steadily increasing in recent years.
Mademlis, Georgios,
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Journal of Marine Science and EngineeringPower electronic converters are an enabling technology for the emerging marine energy applications, such as using ocean waves to produce electricity. This paper outlines the power take-off system and its key components used in a wave energy converter ...
Hamed Nademi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Applied SciencesThis paper presents a thermodynamic analysis of free-turbine turboshaft engines, focusing on the quantitative distribution of turbine power and related energy parameters between the gas generator turbine and the free power turbine.
Răzvan Marius Catană +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
STRUCTURE OF THE TAKE-OFF POWER OF A SKI JUMPER DURING A STATIC TAKE-OFF
, 2017 Namen raziskave je bil ugotoviti povezanost med spremenljivkami odriva smučarja skakalca na skakalnici in spremenljivkami odriva smučarja skakalca pri imitaciji odskoka.
Vodan, Gašper
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Aircraft engine performance and integration in a flying wing aircraft conceptual design [PDF]
, 2012 The increasing demand of more economical and environmentally friendly aero engines leads to the proposal of a new concept – geared turbofan. In this thesis, the characteristics of this kind of engine and relevant considerations of integration on a ...
Miao, Zhisong.
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