Results 41 to 50 of about 124,312 (259)

The power of microRNAs as diagnostic and prognostic biomarkers in liquid biopsies

Cancer Drug Resistance, 2020
In the last decades, progresses in medical oncology have ameliorated the treatment of patients and their outcome. However, further improvements are still necessary, in particular for certain types of tumors such as pancreatic, gastric, and lung cancer as
Lorena Quirico, F. Orso
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Gas-Liquid Agitation with Closed Turbine Type Impellers Modified for Blade Geometries [PDF]

Chemical and Biochemical Engineering Quarterly
An agitation impeller with shrouded blades—specifically, a closed impeller—was redesigned. A closed impeller originating from a conventional turbine-type impeller was analyzed by considering the internal liquid flow characteristics.
M. Yoshida, M. Nakata, K. Itagaki, K. Suganuma, R. Kiyota, S. Kogami, Y. Takahashi   +6 more
doaj   +1 more source

Towards the Development of Miniature Scale Liquid Fuel Combustors for Power Generation Application—A Review

Energies, 2023
As the demand for powerful, light energy sources continues to grow, traditional electrochemical batteries are no longer sufficient and combustion-based power generation devices have become an attractive alternative due to their high energy density ...
Vinay Sankar, Sreejith Sudarsanan, Sudipto Mukhopadhyay, Prabhu Selvaraj, Aravind Balakrishnan, Ratna Kishore Velamati   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A numerical study on capillary-evaporation behavior of porous wick in electronic cigarettes

Scientific Reports, 2021
A mathematical model based on heat and mass transfer processes in the porous wick of electronic cigarettes was established to describe the atomization of e-liquids according to max liquid temperature, vaporization rate and thermal efficiency in a single ...
Yihan Gao, Dian Li, Jiexiong Ru, Muyun Yang, Lehua Lu, Li Lu, Jinlu Wu, Zhonghui Huang, Yan Xie, Naiping Gao   +9 more
doaj   +1 more source

Analysis of the Influence of Thermophysical Properties of a Droplet Liquid on the Work Processes of a Two-Stage Piston Hybrid Power Machine

Machines, 2022
The article considers the influence of the main thermophysical properties of the power liquid on the working processes and energy characteristics of a new highly efficient two-stage piston hybrid power machine designed to compress gas to medium and high ...
Victor Shcherba, Evgeniy Pavlyuchenko, Evgeniy Nosov, Irina Bulgakova   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Power-to-gas and power-to-liquid systems in emerging hydrogen valleys: techno-economic assessment of alternative fuels

Energy Storage and Saving
This study presents a techno-economic assessment of power-to-gas and power-to-liquid pathways within the hydrogen valley concept to support the decarbonization of local energy systems.
Endeshaw Alemu Bekele, Antonio Sgaramella, Alessandro Ciancio, Gianluigi Lo Basso, Livio de Santoli, Lorenzo Mario Pastore   +5 more
doaj   +1 more source

Powering the Future with Liquid Sunshine [PDF]

Joule, 2018
Summary In 2017, global CO2 emissions from burning fossil fuels reached 33 gigatons, twice the natural rate at which CO2 is absorbed back into land and ocean sinks. Harnessing solar radiation holds the answer to reducing our dependence on fossil fuels. It is the most abundant energy resource and could meet humans' future energy needs.
Choon Fong Shih, Tao Zhang, Jinghai Li, Chunli Bai   +3 more
openaire   +1 more source