Results 61 to 70 of about 124,312 (259)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Effects of Asymmetric Gas Distribution on the Instability of a Plane Power-Law Liquid Jet

open access: yesEnergies, 2018
As a kind of non-Newtonian fluid with special rheological features, the study of the breakup of power-law liquid jets has drawn more interest due to its extensive engineering applications.
Jin-Peng Guo   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Diversity in the acceptance of sustainable aviation fuels: Uncovering varying motivational patterns

open access: yesFuel Communications
The aviation sector’s significant contribution to greenhouse gas emissions has spurred interest in sustainable aviation fuels (SAF) as a means to mitigate environmental impact.
Eva-Maria Schomakers   +2 more
doaj   +1 more source

Realisation of DC/DC high power and large current combined power supply for airborne radar

open access: yesThe Journal of Engineering, 2019
With the development of radar power supply system, the power density of DC/DC power supply is becoming larger and larger, but the volume is becoming smaller and smaller, which makes the power density of the power supply increase, and the combination of ...
Yingying Zhang   +7 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Role of power to liquids and biomass to liquids in a nearly renewable energy system

open access: yesIET Renewable Power Generation, 2019
In order to achieve significant greenhouse gas emission reductions, decarbonisation of all economic sectors must be considered. Here, the authors study the provision of renewable energy for the power, district heating, transport and industrial sectors in
J. Ikäheimo   +3 more
semanticscholar   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

The Design and Validation of an Intensity-Modulated Multipoint Fiber-Optic Liquid-Level Sensor

open access: yesSensors
This study introduces a cost-effective solution and sensor arrays for the multipoint liquid-level measuring sensor based on an intensity modulation technique.
Abdul Ghaffar   +9 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

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