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Poxvirus Bioinformatics

2004
Biochemical and functional analysis of poxvirus genomes, genes, and proteins has entered a new era with the recent sequencing of more than 30 poxvirus genomes. The management and analysis of this volume of sequence data in an efficient and effective manner requires specialized computer software.
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Poxvirus Recombinant Vaccines

Annals of the New York Academy of Sciences, 1990
The poxvirus family, subfamily Chordopoxviridae, contains six genera. The basic criteria distinguishing membership in a genus is cross-neutralization and host-range predilection. Members of the genus Orthopoxvirus (vaccinia) and of the genus Avipoxvirus (fowlpox) have been genetically engineered to express genes from heterologous pathogens, thus ...
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Poxvirus Epidemiology

Illnesses caused by poxviruses have plagued humanity for millennia. The most notable are caused by viruses comprising the orthopoxvirus genus. Smallpox (caused by Variola virus) became the first eradicated disease in 1980. Devotion to smallpox eradication required significant orthopoxvirus research and discovery including vaccine and medical ...
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Rifampicin Poxvirus and Trachoma Agent: Rifampicin and Poxvirus Replication

Nature, 1969
Rifampicin appears to inhibit the replication of poxvirus by blocking the synthesis of virus protein late in the growth cycle. The antibiotic inhibits the multiplication of trachoma agent in vitro, and in vivo; it has been used successfully to treat trachoma infection of a baboon's eye. The hydrazone side-chain of rifampicin appears to be essential for
ZVI BEN-ISHAI   +3 more
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Poxvirus Expression Vectors

1992
The poxviruses form a large family of complex DNA viruses that infect both vertebrate and invertebrate hosts. The most notorious member, variola virus, was responsible for smallpox, one of the most dreaded of all infectious diseases. In the late 18th century, Edward Jenner demonstrated that smallpox could be prevented by immunization with a more benign
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Poxvirus DNA

Virology, 1976
J.A. Holowczak, Lee Diamond
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Poxvirus

2022
Rebecca K. Lane, Yan Xiang
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Poxvirus Dilemmas

New England Journal of Medicine, 1998
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