Results 191 to 200 of about 28,925 (227)
Protein phosphatase PP1‐NIPP1 activates mesenchymal genes in HeLa cells [PDF]
FEBS Letters, 2015 The deletion of the protein phosphatase-1 (PP1) regulator known as Nuclear Inhibitor of PP1 (NIPP1) is embryonic lethal during gastrulation, hinting at a key role of PP1-NIPP1 in lineage specification. Consistent with this notion we show here that a mild,
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Science's STKE, 2002
Cramming for an exam is not always the best learning strategy. Studies have suggested that learning across several sessions is much more effective. But even after learning something, we tend to forget it with time and age. Molecular studies have indicated that certain signaling proteins that regulate synaptic strength may underlie ...
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Cramming for an exam is not always the best learning strategy. Studies have suggested that learning across several sessions is much more effective. But even after learning something, we tend to forget it with time and age. Molecular studies have indicated that certain signaling proteins that regulate synaptic strength may underlie ...
openaire +2 more sources
Science's STKE, 2002
Protein phosphatase 1 (PP1) exists in three isoforms encoded by three separate genes: PP1α, PPI β/δ, and PP1γ. Each of these interacts with targeting subunits and has a distinct subcellular localization. However, results with antibody labeling have yielded conflicting results.
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Protein phosphatase 1 (PP1) exists in three isoforms encoded by three separate genes: PP1α, PPI β/δ, and PP1γ. Each of these interacts with targeting subunits and has a distinct subcellular localization. However, results with antibody labeling have yielded conflicting results.
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RETMEN2A and RETMEN2B Oncoproteins are Targets of PP1 Inhibitor
Tumori Journal, 2003Medullary thyroid carcinoma (MTC) responds very poorly to chemotherapy. Mutations in the RET gene are critical for MTC pathogenesis. RET therefore represents a rational target for the development of novel MTC therapies. The accumulation of evidence from laboratory studies strongly suggests that PP1 inhibitor is a cytostatic agent for cells expressing ...
I. Bongarzone +4 more
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Biochemical and biophysical research communications, 1993
cDNA clones for 4 rat protein phosphatase 1 (PP1) catalytic subunit isotypes, PP1 alpha, PP1 gamma 1, PP1 gamma 2 and PP1 delta, were isolated (K. Sasaki et al., Jpn. J. Cancer Res. 81, 1272-1280, 1990). Antibodies were raised to determine the physiological functions of 4 isotypes. Among these isotypes, the PP1 gamma 2 protein was detected specifically
H, Shima +6 more
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cDNA clones for 4 rat protein phosphatase 1 (PP1) catalytic subunit isotypes, PP1 alpha, PP1 gamma 1, PP1 gamma 2 and PP1 delta, were isolated (K. Sasaki et al., Jpn. J. Cancer Res. 81, 1272-1280, 1990). Antibodies were raised to determine the physiological functions of 4 isotypes. Among these isotypes, the PP1 gamma 2 protein was detected specifically
H, Shima +6 more
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Regulation of GSK3 isoforms by phosphatases PP1 and PP2A
Molecular and Cellular Biochemistry, 2010Dephosphorylation of phospho GSK3 isoforms, from COS-7 cells, was determined in vitro and in cultured cells in the absence or the presence of okadaic acid and lithium. Our results indicate a preferential dephosphorylation of phospho GSK3α by PP2A phosphatase, whereas dephosphorylation of phospho GSK3β mainly takes place by PP1 phosphatase.
Hernández, Félix +4 more
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Functional Analysis of PP1 Regulator Phactr1 [PDF]
, 2018 The Phosphatase and actin regulator (Phactr) protein family has been identified as a group of four proteins (Phactr1,2,3,4), interacting with Protein Phosphatase 1 (PP1) and G-actin.
Prechova, M
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PP1 and developmental signalling
Biochemical Society Transactions, 2000D. H. Bennett, B. Szöör, L. S. Alphey
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The impact of Aβ on the Neurabin/PP1 complex
2016O nosso cérebro é uma estrutura complexa constituída por neurónios capazes de comunicar entre si através de sinapses, que geralmente ocorrem entre o terminal axonal e a espinha dendrítica de dois neurónios. Estas espinhas dendríticas são dinâmicas, permitindo assim que se adaptem aos estímulos que recebem, quer estimulantes quer inibitórios.
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