Results 171 to 180 of about 40,152 (210)
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PP2 prevents β-adrenergic stimulation of cardiac pacemaker activity.
Journal of cardiovascular pharmacology, 2015One of the main strategies for cancer therapy is to use tyrosine kinase inhibitors for inhibiting tumor proliferation. Increasing evidence has demonstrated the potential risks of cardiac arrhythmias (such as prolonged QT interval) of these drugs. We report here that a widely used selective inhibitor of Src tyrosine kinases, 4-amino-5-(4-chlorophenyl)-7-
Jianying, Huang +5 more
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The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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Modulation of Cell Adhesion Molecules in Various Epithelial Cell Lines after Treatment with PP2
Molecular Pharmaceutics, 2005Regulation and expression of E-cadherin and other adhesion molecules were evaluated after exposure to a selective inhibitor of the Src family of tyrosine kinases and inducer of E-cadherin, PP2. E-cadherin is located within the intercellular junction, and it is involved in the management of paracellular permeability of various epithelial barriers in the
Anna Maria, Calcagno +6 more
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Apoptotic effect of PP2 a Src tyrosine kinase inhibitor, in murine B cell leukemia
Journal of Cellular Biochemistry, 2004AbstractSrc is a non‐receptor protein tyrosine kinase that transduces signals regulating cell growth and differentiation. We report here that activation of signaling pathway after blockade of tyrosine phosphorylation by PP2 (4‐amino‐5‐(4‐chloro‐phenyl)‐7‐(t‐butyl)pyrazolo[3,4‐d]pyrimidine), a potent and selective inhibitor of the Src‐family tyrosine ...
Michael, Lee +2 more
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PP2 Fiabilité des enquêtes alimentaires chez les patients diabétiques de type 2
Diabetes & Metabolism, 2008Introduction Dans la prise en charge des patients diabetiques de type 2, les conseils hygieno-dietetiques representent une part importante du traitement. Dans le cadre d’un programme d’auto apprentissage en ambulatoire, nous leur apprenons a realiser leur auto enquete alimentaire (AEA) sur 3 jours.
S. Marchand +5 more
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Organisation du phloème et analyse fonctionnelle des protéines PP2.
2012Le phloème est un tissu complexe composé de plusieurs types cellulaires, dont les cellules compagnes et les tubes criblés. Il permet le transport et l’allocation à longue distance de nombreux métabolites et de macromolécules. Il existe dans les tubes criblés des structures très spécifiques dont la fonction est inconnue.
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[PP2 enhances intercellular communication of gap junction in breast cancer Hs578T cells].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2014To investigate the effect of Src kinase inhibitor PP2 on intercellular communication of gap junction in breast cancer cells.Cultured breast cancer Hs578T cells were treated with various concentrations of pp2 (0,1,2,4,8,16,32 μmol/L) for 24h. Cell growth was determined by MTT assay; dye spread in Hs578T cells was measured by Parachute assay; and the ...
Shu-Ying, Dong +4 more
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