Results 161 to 170 of about 114,575 (218)

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Generation of a glycogen storage disease mouse model with fatty liver and its treatment by PPAR-α agonist bezafibrate. [PDF]

Front Pharmacol
Xie Y, Fu G, Fan C, Huang H, Yan J, Jin L.   +5 more
europepmc   +1 more source

Pemafibrate Improves Cholestatic Markers Regardless of the Presence of Primary Biliary Cholangitis

Hepatology Research, EarlyView.
Pemafibrate improves liver function markers related to bile flow in primary biliary cholangitis (PBC), but whether this effect is disease‐specific remains unclear. In this study, pemafibrate reduced these markers in patients with and without PBC, suggesting broader effects on bile flow beyond PBC.
Ryohei Tanigawa, Yoshiyuki Ueno, Hirokazu Takahashi, Ayumi Saito, Hideki Suganami, Atsushi Tanaka   +5 more
wiley   +1 more source

Efficacy, symptoms, and safety of second-line PBC therapies: a network meta-analysis. [PDF]

Front Pharmacol
Zhao W, Wu Z, Kou Q, Qiao S, Liu Z, Zhang X.   +5 more
europepmc   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

International Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta, Kamilla Yamileva, Laura Punakallio, Maryam Ghanbarirad, Evgen Multia   +4 more
wiley   +1 more source

Immune cell remodelling and the peribiliary immune niche in primary biliary cholangitis: from initiation to chronicity. [PDF]

eGastroenterology
Xiong J, Zhang Z, Zhang Z, Yuan M, Zhu K, Wang FS, Shi L.   +6 more
europepmc   +1 more source

Cardiovascular preventive role of thiazolidinedione in patients with type 2 diabetes mellitus undergoing percutaneous coronary intervention

Journal of Diabetes Investigation, EarlyView.
Among patients with type 2 diabetes undergoing percutaneous coronary intervention, thiazolidinedione use was independently associated with a significantly reduced risk of a composite of myocardial infarction, stroke, and all‐cause death, notably without an increased risk of admission for heart failure. ABSTRACT Background Thiazolidinediones (TZD) are a
Jinkwon Kim, Jimin Jeon, Joonsang Yoo, Minyoul Baik, Seok‐Jae Heo, Ji Woong Roh   +5 more
wiley   +1 more source

The application of nanoparticles green-formulated by Lycium barbarum leaf aqueous extract in the treatment of myocardial infarction. [PDF]

Discov Nano
Liu Y, Gao F, Kong Y, Li X.
europepmc   +1 more source

Fasting serum annexin A2 is associated with peripheral insulin sensitivity and may enhance glucose uptake via Src‐dependent signaling

Journal of Diabetes Investigation, EarlyView.
Circulating Annexin A2 is positively associated with peripheral insulin sensitivity. ABSTRACT Background and Aim Subcellular annexin A2 (ANXA2) is known to regulate membrane dynamics and GLUT4 trafficking in adipocytes; however, the role of serum ANXA2 in glucose metabolism remains unclear.
Yuichi Ito, Tsuyoshi Okura, Mari Anno, Sonoko Kitao, Satomi Endo, Yoshinori Ichihara, Tatsuya Sawano, Junichiro Miake, Etsuko Ueta, Masahiko Kato, Shin‐ichi Taniguchi, Kazuhiro Yamamoto, Takeshi Imamura   +12 more
wiley   +1 more source

Thiazolidinedione Use and Risk of Bacterial Enteric Infection Among Adults With Type 2 Diabetes Mellitus. [PDF]

Open Forum Infect Dis
Birabaharan M, Kaelber DC, Nizet V, Zarrinpar A.   +3 more
europepmc   +1 more source