Results 151 to 160 of about 23,167 (255)

Integrative multi-omics and network analysis identify potential targets of Chaihu Shugan Xiaozheng Formula in breast cancer. [PDF]

Transl Oncol
Luo T, Xue M, Du Y, Chen H, Sun Y, Sun H.   +5 more
europepmc   +1 more source

Effects of proton therapy on the tumor immune system and clinical implications: A review

Precision Radiation Oncology, EarlyView.
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu, Mei Tao, Min Fu, Yingjia Hu, Zhen Tao, Guangyuan Hu   +5 more
wiley   +1 more source

METTL14 inhibits atherogenesis by epigenetically activating PPAR-α/γ transcription and fatty acid oxidation in VSMCs. [PDF]

Cardiovasc Res
Cui L, Ho CK, Liang P, Gao W, Liu J, Tian XY, Wong R, Zhou B, Lui KO.   +8 more
europepmc   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Diffuse pediatric-type high grade glioma, RTK1 subtype, subclass C with <i>SYN2</i>::<i>PPARG</i> fusion in an older adult. [PDF]

CNS Oncol
Brentlinger MN, Patel J, Khan A, Castro-Echeverry E, Abdullaev Z, Aldape K, Lehman NL.   +6 more
europepmc   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

Phytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li, Yang‐Chi‐Dung Lin, Hsi‐Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien‐Da Huang   +6 more
wiley   +1 more source

New PPARG Exons: Cell-Specific Expression of Their RNAs in the Human Placenta. [PDF]

Cells
Vignaud ML, Morin N, Fournier T.
europepmc   +1 more source

Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling

Phytotherapy Research, EarlyView.
Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf, Ayfer Busra Benkli, Ramiz Yusuf   +2 more
wiley   +1 more source

SPP1+ Macrophages Involved in Juvenile Xanthogranuloma via PPARG Signaling Pathway. [PDF]

J Inflamm Res
Yuan X, Li J, Zhang X, Zhang H, Li P, Liu M, Chen H, Liu R, Zhu S, Feng S, Xiao X, Xing Z, Huang X, Wang C, Tang P.   +14 more
europepmc   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source