Results 1 to 10 of about 17,878 (217)
PPARs as Nuclear Receptors for Nutrient and Energy Metabolism
Molecules, 2019 It has been more than 36 years since peroxisome proliferator-activated receptors (PPARs) were first recognized as enhancers of peroxisome proliferation. Consequently, many studies in different fields have illustrated that PPARs are nuclear receptors that
Pengfei Xu, Yonggong Zhai, Shijia Pan
exaly +3 more sources
Cells, 2021 Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors including PPARα, PPARγ, and PPARβ/δ, acting as transcription factors to regulate the expression of a plethora of target genes involved in metabolism, immune reaction ...
Rosa Maria Vitale, Fabio Arturo Iannotti
exaly +3 more sources
Russian Open Medical Journal, 2023 Publication interest in cannabinoids, including phytocannabinoids, endogenous cannabinoids, synthetic cannabinoids and cannabinomimetic compounds, is due to the therapeutic potential of these compounds in inflammatory pathology.
Oksana Yu. Kytikova +3 more
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International Journal of Medical Biochemistry, 2022 INTRODUCTION: Nicotine is a substance associated with rewarding and abusive effects. The rewarding effects of nicotine are thought to be due to dopamine signaling, which is negatively controlled through peroxisome proliferator-activated receptors (PPARs).
Andleeb Shahzadi, Sibel Ozyazgan
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Molecules, 2020 Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with three isoforms (PPARα, PPARβ/δ, PPARγ) and can regulate pain, anxiety, and cognition.
Jessica C. Gaspar +4 more
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The Role of PPARs in Breast Cancer
Cells, 2022 Breast cancer is a malignant tumor with high morbidity and lethality. Its pathogenesis is related to the abnormal expression of many genes. The peroxisome proliferator-activated receptors (PPARs) are a class of ligand-dependent transcription factors in ...
Binggong Zhao +3 more
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PPAR-Mediated Toxicology and Applied Pharmacology
Cells, 2020 Peroxisome proliferator-activated receptors (PPARs), members of the nuclear hormone receptor family, attract wide attention as promising therapeutic targets for the treatment of multiple diseases, and their target selective ligands were also intensively ...
Yue Xi +5 more
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SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway
BMC Cancer, 2023 Background Peroxisome proliferator activated receptors (PPARs) are a nuclear hormone receptors superfamily that is closely related to fatty acid (FA) metabolism and tumor progression.
Kun Shang +6 more
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Marine Drugs, 2019 Oxidative stress contributes to chronic inflammatory processes implicated in aging, referred to as “inflamm-aging.” In this study, the potential anti-inflammatory and anti-aging effects of a pigment−protein complex (PPC) from Chlorella ...
Ruilin Zhang +4 more
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Peptide Helix-Y12 as Potential Effector for Peroxisome Proliferator-Activated Receptors
PPAR Research, 2023 Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in the regulation of lipids and glucose metabolism, and immune response. Therefore, they have been considered pharmacological targets for treating metabolic diseases, such
Mauricio Carrillo-Tripp +4 more
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