Results 121 to 130 of about 112,621 (284)

A Conceptual Disease Model of Symptoms and Impacts in Adults with Prurigo Nodularis: A Qualitative and Literature-Informed Study

Dermatology and Therapy
Introduction Prurigo nodularis (PN) is a rare neuroimmune inflammatory skin condition characterized by intense, chronic pruritus that can greatly reduce quality of life. Treatment decisions are based on clinical judgment, considering individual patients’
Shawn G. Kwatra, Danielle Rodriguez, Carla Dias-Barbosa, Christophe Piketty, Rajesh Rout, Ramkumar Subramanian, Jorge Puelles   +6 more
doaj   +1 more source

Premenstrual syndrome as a risk factor for postpartum depression

Акушерство, гинекология и репродукция
Aim: to identify a possible association between postpartum depression (PPD) and symptoms of premenstrual syndrome (PMS).Materials and Methods. A total of 296 women who completed pregnancy to delivery initially agreed to participate in the cohort study ...
A. Е. Sidorov, T. G. Denisova, N. V. Zhuravleva   +2 more
doaj   +1 more source

The association of periodontal inflammation and inflammatory markers with cognitive dysfunction: A case–control study

Journal of Periodontology, EarlyView.
Abstract Background This study investigated the association of inflammatory markers in saliva, plasma, and cerebrospinal fluid (CSF) with cognitive decline and periodontitis. Methods Patients with Alzheimer disease (AD, n = 52), mild cognitive impairment (MCI, n = 51), subjective cognitive decline (SCD, n = 51), and controls (n = 76) between 50 and 80 ...
Kåre Buhlin, Maria Eriksdotter, Leif Jansson, Pirkko J. Pussinen, Marianne Schultzberg, Ronaldo Lira‐Junior   +5 more
wiley   +1 more source

Patient preferences for the benefits and risks of insomnia medication in a clinical trial and real-world setting

Sleep Science and Practice
Background The PAtient preferences stUdy in inSomnia (PAUSe) sub-study used a discrete choice experiment (DCE) to assess treatment preferences in patients with chronic insomnia who participated in randomized, placebo-controlled trials (NCT03545191 or ...
Andrea Phillips Beyer, Melissa Ross, Martin Katzman, Antonio Olivieri, Sebastian Heidenreich   +4 more
doaj   +1 more source

Long‐term clinical benefits of periodontal interventions in strict supportive periodontal care: A systematic review

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis requires long‐term management to prevent recurrence and tooth loss. While active periodontal therapy (APT) aims to reduce probing pocket depth (PPD) and improve clinical attachment level (CAL), strict supportive periodontal care (SPC) is essential for maintaining these clinical outcomes.
Varkha Rattu, Tishani Patel, Jasmine Loke, Hari Petsos, Luigi Nibali   +4 more
wiley   +1 more source

The influence of flap design on the relevance of biomaterials in regenerative periodontal surgery

Journal of Periodontology, EarlyView.
Abstract Background The aim of this systematic review was to explore whether the benefits of biomaterials in periodontal regenerative/reconstructive surgery are affected by the type of flap employed. The study addresses the existing gap in the evidence to substantiate the beneficial effect of minimal invasive periodontal surgical approach compared to a
Payvand Menhadji, Neha Kansagra, Luigi Nibali   +2 more
wiley   +1 more source

Clinical Pharmacokinetics and Safety of Orally Administered VH4011499, a New HIV-1 Capsid Inhibitor, in Adults Without HIV

Infectious Diseases and Therapy
Introduction This first-time-in-human study describes the pharmacokinetics, drug–drug interaction potential, and safety of VH4011499 (VH-499), a new HIV-1 capsid inhibitor.
Nilay Thakkar, Rulan Griesel, Amy Pierce, Veronica Bainbridge, Bronagh Shepherd, Konstantinos Angelis, Andrew Tomlinson, Yash Gandhi, Darin Brimhall, Brian Spears, Daijha Anderson, Emma Pinnick, Carolina Acuipil, Cynthia McCoig, Mark Baker, Paul Benn   +15 more
doaj   +1 more source

Shortened outreach periodontal therapy in nursing home residents with periodontitis: A randomized controlled trial

Journal of Periodontology, EarlyView.
Abstract Background We examined the clinical effectiveness of shortened outreach periodontal therapy for 3 months in nursing home residents with periodontitis versus controls (no therapy). Methods Nursing home residents with periodontitis were randomly assigned to either (a) one‐time, shortened outreach periodontal therapy adapted to German statutory ...
Anna G. Barbe, Dalia Beck, Martin Hellmich, Max von Kohout, Sonja H. M. Derman, Dirk Bleiel   +5 more
wiley   +1 more source

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos, Alba Regueira‐Iglesias, Berta Suárez‐Rodríguez, Alba Sánchez‐Barco, Iryna Kuz, Marta Relvas, Susana Belén Bravo, Carlos Balsa‐Castro, Inmaculada Tomás   +8 more
wiley   +1 more source

A retrospective cohort study comparing periodontal regeneration using fibroblast growth factor‐2 versus autologous bone graft

Journal of Periodontology, EarlyView.
Abstract Background Fibroblast growth factor‐2 (FGF‐2) is a novel agent utilized in periodontal regeneration therapy. However, its clinical efficacy compared with autologous bone graft (ABG), a long‐established treatment, remains unclear. This study aimed to compare the clinical outcomes of FGF‐2 and ABG and to assess the impact of patient background ...
Toshiki Matsumoto, Shin Nakamura, Yuki Ito‐Shinoda, Mai Sakamoto, Takayuki Ishii, Yasuki Nonomura, Hidetaka Ideguchi, Keisuke Okubo, Kazu Takeuchi‐Hatanaka, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba   +11 more
wiley   +1 more source