Results 121 to 130 of about 113,385 (285)

The association of periodontal inflammation and inflammatory markers with cognitive dysfunction: A case–control study

Journal of Periodontology, EarlyView.
Abstract Background This study investigated the association of inflammatory markers in saliva, plasma, and cerebrospinal fluid (CSF) with cognitive decline and periodontitis. Methods Patients with Alzheimer disease (AD, n = 52), mild cognitive impairment (MCI, n = 51), subjective cognitive decline (SCD, n = 51), and controls (n = 76) between 50 and 80 ...
Kåre Buhlin, Maria Eriksdotter, Leif Jansson, Pirkko J. Pussinen, Marianne Schultzberg, Ronaldo Lira‐Junior   +5 more
wiley   +1 more source

Clinical Pharmacokinetics and Safety of Orally Administered VH4011499, a New HIV-1 Capsid Inhibitor, in Adults Without HIV

Infectious Diseases and Therapy
Introduction This first-time-in-human study describes the pharmacokinetics, drug–drug interaction potential, and safety of VH4011499 (VH-499), a new HIV-1 capsid inhibitor.
Nilay Thakkar, Rulan Griesel, Amy Pierce, Veronica Bainbridge, Bronagh Shepherd, Konstantinos Angelis, Andrew Tomlinson, Yash Gandhi, Darin Brimhall, Brian Spears, Daijha Anderson, Emma Pinnick, Carolina Acuipil, Cynthia McCoig, Mark Baker, Paul Benn   +15 more
doaj   +1 more source

Long‐term clinical benefits of periodontal interventions in strict supportive periodontal care: A systematic review

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis requires long‐term management to prevent recurrence and tooth loss. While active periodontal therapy (APT) aims to reduce probing pocket depth (PPD) and improve clinical attachment level (CAL), strict supportive periodontal care (SPC) is essential for maintaining these clinical outcomes.
Varkha Rattu, Tishani Patel, Jasmine Loke, Hari Petsos, Luigi Nibali   +4 more
wiley   +1 more source

The influence of flap design on the relevance of biomaterials in regenerative periodontal surgery

Journal of Periodontology, EarlyView.
Abstract Background The aim of this systematic review was to explore whether the benefits of biomaterials in periodontal regenerative/reconstructive surgery are affected by the type of flap employed. The study addresses the existing gap in the evidence to substantiate the beneficial effect of minimal invasive periodontal surgical approach compared to a
Payvand Menhadji, Neha Kansagra, Luigi Nibali   +2 more
wiley   +1 more source

Shortened outreach periodontal therapy in nursing home residents with periodontitis: A randomized controlled trial

Journal of Periodontology, EarlyView.
Abstract Background We examined the clinical effectiveness of shortened outreach periodontal therapy for 3 months in nursing home residents with periodontitis versus controls (no therapy). Methods Nursing home residents with periodontitis were randomly assigned to either (a) one‐time, shortened outreach periodontal therapy adapted to German statutory ...
Anna G. Barbe, Dalia Beck, Martin Hellmich, Max von Kohout, Sonja H. M. Derman, Dirk Bleiel   +5 more
wiley   +1 more source

Comparison of PPD and IGST Sensitivity in Latent Tuberculosis Assessment (Cross-sectional Study)

Sakarya Tıp Dergisi
Objective: Purified Protein Derivative (PPD) and Interferon Gamma Release Assay (IGRA) were performed on patients with ankylosing spondylitis and rheumatoid arthritis who were planned to initiate immunosuppressive treatment.
Nurhan Sarıoğlu, Nilay Şahin, Mustafa Çolak, Kazım Batıhan Büyükzengin, Fuat Erel, Hikmet Çoban   +5 more
doaj   +1 more source

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos, Alba Regueira‐Iglesias, Berta Suárez‐Rodríguez, Alba Sánchez‐Barco, Iryna Kuz, Marta Relvas, Susana Belén Bravo, Carlos Balsa‐Castro, Inmaculada Tomás   +8 more
wiley   +1 more source

A retrospective cohort study comparing periodontal regeneration using fibroblast growth factor‐2 versus autologous bone graft

Journal of Periodontology, EarlyView.
Abstract Background Fibroblast growth factor‐2 (FGF‐2) is a novel agent utilized in periodontal regeneration therapy. However, its clinical efficacy compared with autologous bone graft (ABG), a long‐established treatment, remains unclear. This study aimed to compare the clinical outcomes of FGF‐2 and ABG and to assess the impact of patient background ...
Toshiki Matsumoto, Shin Nakamura, Yuki Ito‐Shinoda, Mai Sakamoto, Takayuki Ishii, Yasuki Nonomura, Hidetaka Ideguchi, Keisuke Okubo, Kazu Takeuchi‐Hatanaka, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba   +11 more
wiley   +1 more source

Periodontitis severity and its social and clinical determinants: An ACES framework‐based NHANES analysis

Journal of Periodontology, EarlyView.
Abstract Objectives To assess associations between the poverty‐income ratio (PIR) and periodontitis severity using Application of the 2018 Periodontal Status Classification to Epidemiological Survey Data (ACES) framework. Methods Three NHANES cycles (2009–2014) with adults aged ≥30 years with complete periodontal examinations (n = 10,598) were included.
Meng Xuan Chen, Yue Yu, Chen Xuan Wei, Hamoun Sabri, Muhammad H. A. Saleh   +4 more
wiley   +1 more source

Digital and tomographic identification of risk indicators for gingival recession in the mandibular anterior region: A cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background To assess clinical and anatomical risk indicators for mid‐buccal gingival recessions (GRs) in the mandibular anterior region using digital and tomographic tools. Methods A cross‐sectional study was conducted on 103 patients (618 teeth).
Gonzalo Blasi, Lise Maury, Lory Abrahamian, Youssra Abarchan, Behnam Taghavi, Jose Nart   +5 more
wiley   +1 more source