Results 51 to 60 of about 528,172 (313)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

sj-docx-1-ppm-10.1177_00910260221140398 – Supplemental material for Span of Control and Ethical Leadership in Highly Professionalized Public Organizations

, 2022
Supplemental material, sj-docx-1-ppm-10.1177_00910260221140398 for Span of Control and Ethical Leadership in Highly Professionalized Public Organizations by Didde Cramer Jensen, Ane-Kathrine Lundberg Hansen, Lars Dahl Pedersen and Lotte Bøgh Andersen in ...
Didde Cramer Jensen (14254768), Lars Dahl Pedersen (14254774), Ane-Kathrine Lundberg Hansen (14254771), Lotte Bøgh Andersen (6064457)   +3 more
core   +1 more source

Solvent solutions: comparing extraction methods for edible oils and proteins in a changing regulatory landscape. Part 3: Impacts on the process☆

Oilseeds and fats, crops and lipids
This article constitutes the third instalment in a comprehensive series dedicated to the comparative analysis of solvent solutions for oilseeds extraction.
Carré Patrick, Gärtner Maike, Bothe Sarah, Piofczyk Thomas, Hadjiali Sara   +4 more
doaj   +1 more source

PENGARUH REFERENCE GROUPS DALAM PENGAMBILAN KEPUTUSAN MEMBELI KONSUMEN PRODUK KECANTIKAN

Journal of Management and Business Review, 2018
Tujuan penelitian ini adalah terpetakannya reference group paling kuat dalam pengambilan keputusan membeli konsumen produk kecantikan. Metode penelitian yang dilakukan adalah kuantitatif dengan pendekatan analisis deskriptif.
Kartika Yuniarti, Abdus Somad
doaj   +1 more source

PPM 100

, 2023
Dalam rangka meningkatkan mutu pelayanan dosen khususnya Tridarma perguruan tinggi diperlukan pengakuan kinerja sehingga dosen yang bersangkutan dapat meningkatkan kinerjanya.
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

PENGUNGKAPAN CSR DAN CERMINAN ABNORMAL RETURN PERUSAHAAN

Journal of Management and Business Review, 2019
Kajian terkait corporate social responsibility (CSR) berkembang pesat seiring dengan dukungan pemerintahan dalam menciptakan lingkungan bisnis yang bersaing. Dukungan pemerintahan tercermin dalam Undang-Undang No.40 Tahun 2007 tentang Perseroan Terbatas (
Desmon Daniel, Martdian Ratnasari
doaj   +1 more source

Analisis Hubungan Karakteristik Dark Triad dengan Kecenderungan Terjadinya Fraudulent Financial Statement

Journal of Management and Business Review, 2023
Fraud is a global phenomenon with detrimental consequences, especially in financial reporting. However, most research has narrowly focused on financial aspects.
Katarina Siena Herlika Cerline, Indah Sulistyawati Widiarti, Penta Parafina, Martdian Ratna Sari, Noveri Maulana   +4 more
doaj   +1 more source

PPM 114

, 2023
Dalam rangka meningkatkan mutu pelayanan dosen khususnya Tridarma perguruan tinggi diperlukan pengakuan kinerja sehingga dosen yang bersangkutan dapat meningkatkan kinerjanya.
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source