Results 51 to 60 of about 51,645 (262)

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Estimativa e Propagação de Valores de DCB C1C-C2W de um Receptor GPS com Vistas a Correção de Ordem Superior do Efeito Ionosférico

Revista Brasileira de Cartografia, 2020
Quando se almeja maior acurácia no posicionamento GNSS, é imprescindível a correção dos efeitos de ordem superior da refração ionosférica. O erro associado à ionosfera é diretamente proporcional ao conteúdo total de elétrons (Total Electron Content – TEC)
Fabiane Piovesan de Moraes Cordeiro, Tiago Lima Rodrigues, Luiz Danilo Damasceno Ferreira   +2 more
doaj   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

Despojos y formas de agenciar futuro en América Latina

Revista Controversia
La elaboración de este dossier para el número 223 de la revista concatenó diversas controversias y particularidades, producto de la confluencia de nutridos debates interdisciplinarios. El mismo nombre de la revista nos invitaba a considerar un horizonte
Anderson Villa Beltrán, Carolina Céspedes Arce, Cristian Llanos   +2 more
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

NAVIGATING THE RISKS OF PUBLIC- PRIVATE PARTNERSHIPS: CHALLENGES AND MITIGATION STRATEGIES [PDF]

Eastern European Journal of Regional Studies
This study explores the obstacles and risks that Public-Private Partnerships (PPPs) encounter in carrying out economic development initiatives, across Romanian nations.
Elena BIZIM (SURDU)
doaj   +1 more source

Partial Phase‐Separation in the Initial Growth Stage of Exsolution‐Active SrTi0.95‐xNi0.05NbxO3‐δ Thin Films

Advanced Science, EarlyView.
Phase separation emerges during the initial growth of heavily Ni‐ and Ni,Nb‐co‐doped STO thin films, leading to preferential accumulation of Ni and embedded NiOx nanoinclusions in thicker films. Nb co‐doping partially suppresses the ordering of these embedded structures, comprising about 20% of all Ni ions.
Yen‐Po Liu, Moritz L. Weber, Dylan Jennings, Leonid L. Rusevich, Eugene Kotomin, Rainer Timm, Felix Gunkel, Regina Dittmann   +7 more
wiley   +1 more source

Chemical‐Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration

Advanced Science, EarlyView.
M2N2ACa is an innovative injectable thermoresponsive barrier membrane adhesive to achieve reliable bone graft fixation. It provides strong wet adhesion and promotes the bio‐stabilization mediated by coagulation through controlled calcium release. This dual‐fixation strategy combines external chemical fixation and internal biological fixation via clot ...
Yu‐zhu Wang, Gao‐peng Dang, Zhi‐ting Li, Zhi‐hong Feng, Que Bai, Jia‐xin Hao, Xiao‐qing Cao, Tao Ye, Jing Li, Franklin R. Tay, Malcolm Xing, Ming Fang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Implementação de um sistema on-line para processamento de dados GNSS

Revista Brasileira de Cartografia, 2019
O processamento de dados do Global Navigation Satellite System (GNSS) realizado por softwares científicos é uma necessidade crescente nos estudos da Geodésia Espacial. Porém, o manuseio destes, em geral, nem sempre é uma tarefa fácil.
Gabriel Diniz de Oliveira, William Rodrigo Dal Poz, Marília Sanglard Almeida   +2 more
doaj   +1 more source

Logic Functionality and Circuit Design of In2Se3‐Based Split‐Gate Ferroelectric Field‐Effect Transistor for Zero‐Trust Applications

Advanced Electronic Materials, EarlyView.
ABSTRACT Van der Waals ferroelectric materials are emerging as key building blocks for future logic devices and integrated circuits. Among them, α‐In2Se3 offers a unique combination of robust room temperature ferroelectricity and semiconducting behavior.
Ankita Ram, Cédric Marchand, Shehr Bano Masood, Aymen Mahmoudi, Takashi Taniguchi, Kenji Watanabe, Bernard Doudin, Abdelkarim Ouerghi, Ian O'Connor, Alexei Gruverman, Jean‐François Dayen   +10 more
wiley   +1 more source