Results 51 to 60 of about 352,706 (306)

¿A qué partidos se llevó el viento en Colombia? Aproximaciones al auge y la decadencia del bipartidismo colombiano

open access: yesRevista Controversia, 2011
El artículo discute diferentes aproximaciones sobre la crisis actual de los partidos Conservador y Liberal de Colombia, contrastando interpretaciones de tipo estructural con otras que privilegian el análisis coyuntural de mediano y corto plazos. A partir
Fernán González
doaj  

Detection of Structural Vibration with High-Rate Precise Point Positioning: Case Study Results Based on 100 Hz Multi-GNSS Observables and Shake-Table Simulation

open access: yesSensors, 2019
This contribution presents and assesses the methodology aiming at the characterization of the structural vibrations with high-rate GNSS measurements.
Jacek Paziewski   +2 more
doaj   +1 more source

PPP-Completeness with Connections to Cryptography [PDF]

open access: yes, 2018
Polynomial Pigeonhole Principle (PPP) is an important subclass of TFNP with profound connections to the complexity of the fundamental cryptographic primitives: collision-resistant hash functions and one-way permutations.
Sotiraki, Katerina   +2 more
core   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

open access: yesAdvanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng   +10 more
wiley   +1 more source

Local Chemical Gradients in a Mammalian Cortex Measured In Vivo With a Silicon Nanodialysis Mass Spectrometry Platform

open access: yesAngewandte Chemie, EarlyView.
Fluorescence image of the coronal slice of mouse brain where multiple neurochemicals have been measured in vivo with a nanodialysis platform coupled to CE‐MS to reveal strong millimeter‐scale spatial chemical gradients. Formation and maintenance of such local chemical compartments in the otherwise diffusion‐homogeneous cortex indicates strong ...
Weihua Shi   +5 more
wiley   +2 more sources

Epidemiological Determinants of Acute Respiratory Syndrome Coronavirus-2 Disease Pandemic and The Role of the Bacille-Calmette-Guerin Vaccine in Reducing Morbidity and Mortality

open access: yesJournal of Pure and Applied Microbiology, 2020
This study analyzed the determinants of morbidity, mortality, and case fatality rate (CFR) of the ongoing pandemic of severe acute respiratory syndrome coronavirus-2 disease 2019 (COVID-19).
Bhoj R. Singh   +10 more
doaj   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu   +8 more
wiley   +1 more source

NAVIGATING THE RISKS OF PUBLIC- PRIVATE PARTNERSHIPS: CHALLENGES AND MITIGATION STRATEGIES [PDF]

open access: yesEastern European Journal of Regional Studies
This study explores the obstacles and risks that Public-Private Partnerships (PPPs) encounter in carrying out economic development initiatives, across Romanian nations.
Elena BIZIM (SURDU)
doaj   +1 more source

Empirical Testing of Purchasing Power Parity Validity in Selected European Union Countries

open access: yesNaše Gospodarstvo, 2021
In this article, the authors carried out an empirical analysis of the validity of purchasing power parity (PPP) in Slovenia, Croatia, the Czech Republic, Slovakia and Austria.
Plošinjak Jelko, Festić Mejra
doaj   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

open access: yesAdvanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty   +21 more
wiley   +1 more source

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