Results 1 to 10 of about 3,280 (219)

Genetic analyses and functional validation of ruminant SLAMs reveal potential hosts for PPRV [PDF]

Veterinary Research
Peste des petits ruminants (PPR), caused by the peste des petits ruminants virus (PPRV), is a highly contagious disease affecting ruminants. While goats and sheep are well-known hosts, PPRV has also spread to wild ruminants, and it remains unclear which ...
Xi Wei, Kejia Lu, Zhengwu Chang, Hanwei Guo, Qinfeng Li, Binxuan Yuan, Chen Liu, Zengqi Yang, Haijin Liu   +8 more
doaj   +8 more sources

The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication [PDF]

mBio
Peste des petits ruminants virus (PPRV) is an important pathogen that has long been a significant threat to small ruminant productivity worldwide. Iron metabolism is vital to the host and the pathogen.
Bo Wen, Wenchi Chang, Lulu Yang, Daiyue Lv, Lizhen Wang, Lei Wang, Yanzhao Xu, Jianhe Hu, Ke Ding, Qinghong Xue, Xuefeng Qi, Bo Yang, Jingyu Wang   +12 more
doaj   +3 more sources

A Single Dose of Live-Attenuated Rift Valley Fever Virus Vector Expressing Peste Des Petits Ruminants Virus (PPRV) H or F Antigens Induces Immunity in Sheep [PDF]

Vaccines
Introduction/Background: Rift Valley fever virus (RVFV) and peste des petits ruminants virus (PPRV) are significant pathogens affecting small ruminants, causing substantial economic losses in the affected regions.
Sandra Moreno, Gema Lorenzo, Verónica Martín, Celia Alonso, Friedemann Weber, Belén Borrego, Alejandro Brun   +6 more
doaj   +3 more sources

Peste des petits ruminants virus (PPRV) induces ferroptosis via LONP1-mediated mitochondrial GPX4 degradation in cell culture [PDF]

Journal of Virology
Peste des petits ruminants virus (PPRV) is an important pathogen that seriously affects the productivity of small ruminants worldwide. Ferroptosis is a programmed cell death characterized by iron-dependent lipid peroxidation and the accumulation of ...
Qiaodi Hou, Shuijin Cheng, Zhijun Li, Congshang Lei, Yan Chen, Mingzhuo Ma, Jinming Liu, Xiwen Chen, Lizhen Wang, Qinghong Xue, Xuefeng Qi   +10 more
doaj   +3 more sources

Vaccination with recombinant adenovirus expressing peste des petits ruminants virus-F or -H proteins elicits T cell responses to epitopes that arises during PPRV infection [PDF]

Veterinary Research, 2017
Peste des petits ruminants virus (PPRV) causes an economically important disease that limits productivity in small domestic ruminants and often affects the livestock of the poorest populations in developing countries.
José Manuel Rojas, Miguel Avia, Elena Pascual, Noemí Sevilla, Verónica Martín   +4 more
doaj   +2 more sources

Vaccination with recombinant adenoviruses expressing the peste des petits ruminants virus F or H proteins overcomes viral immunosuppression and induces protective immunity against PPRV challenge in sheep. [PDF]

PLoS ONE, 2014
Peste des petits ruminants (PPR) is a highly contagious disease of small ruminants caused by the Morbillivirus peste des petits ruminants virus (PPRV). Two recombinant replication-defective human adenoviruses serotype 5 (Ad5) expressing either the highly
José M Rojas, Héctor Moreno, Félix Valcárcel, Lourdes Peña, Noemí Sevilla, Verónica Martín   +5 more
doaj   +3 more sources

Genomic characterization and evolution analysis of peste des petits ruminants virus in China from 2007 to 2024 [PDF]

Frontiers in Microbiology
Peste des petits ruminants (PPR) is a highly contagious and lethal disease, primarily affecting sheep, goats, and wild small ruminants. Genomic characterization and evolutionary analysis of the circulating PPR virus (PPRV) strains can provide valuable ...
Jingyue Bao, Ruiying Jiang, Ruiying Jiang, Shujuan Wang, Qinghua Wang, Jiao Xu, Yunling Zhao, Yutian Liu, Lin Li, Xiaohua Wang, Zhiliang Wang   +10 more
doaj   +2 more sources

Detection of canine distemper virus (CDV) neutralising antibodies in small ruminants during peste-des-petits-ruminants virus (PPRV) surveillance in Zambia [PDF]

BMC Veterinary Research
Canine distemper virus (CDV) is endemic in Zambia, while peste-des-petits-ruminants virus (PPRV) has not been detected. This study screened 962 farmed goats and 237 small ruminants at informal markets for PPRV antibodies using c-ELISA.
Sara Lysholm, Nicola Logan, Johanna F Lindahl, Mikael Berg, Elin Johansson, Pernilla Karlsson Bergkvist, George Dautu, Ricky Chazya, Brian J. Willett, Musso Munyeme, Jonas Johansson Wensman   +10 more
doaj   +2 more sources

A phosphoprotein gene RT-qPCR assay for detecting all lineages of peste des petits ruminants virus [PDF]

Frontiers in Microbiology
Peste des petits ruminants (PPR) is a highly contagious disease caused by peste des petits ruminants virus (PPRV). PPRV is classified into four lineages based on the nucleocapsid (N) or fusion (F) genes.
Jiao Xu, Yonggang Zhao, Huicong Li, Qinghua Wang, Jiarong Yu, Yingli Wang, Jingyue Bao, Zhiliang Wang   +7 more
doaj   +2 more sources

Empirical and model-based evidence for a negligible role of cattle in peste des petits ruminants virus transmission and eradication [PDF]

Communications Biology
Peste des petits ruminants virus (PPRV) is a multi-host pathogen with sheep and goats as main hosts. To investigate the role of cattle in the epidemiology of PPR, we simulated conditions similar to East African zero-grazing husbandry practices in a ...
Catherine M. Herzog, Fasil Aklilu, Demeke Sibhatu, Dereje Shegu, Redeat Belaineh, Abde Aliy Mohammed, Menbere Kidane, Claudia Schulz, Brian J. Willett, Sarah Cleaveland, Dalan Bailey, Andrew R. Peters, Isabella M. Cattadori, Peter J. Hudson, Hagos Asgedom, Joram Buza, Mesfin Sahle Forza, Tesfaye Rufael Chibssa, Solomon Gebre, Nick Juleff, Ottar N. Bjørnstad, Michael D. Baron, Vivek Kapur   +22 more
doaj   +2 more sources