Results 21 to 30 of about 1,347 (114)

Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication

Frontiers in Veterinary Science, 2021
Peste des petits ruminant virus (PPRV) causes a highly contagious disease in small ruminants. The molecular mechanism of PPRV replication and its interactions with hosts are poorly studied.
Niyokwishimira Alfred, Niyokwishimira Alfred, Bang Qian, Xiaodong Qin, Xiangping Yin, Meera Prajapati, Meera Prajapati, Yongxi Dou, Yanmin Li, Zhidong Zhang   +9 more
doaj   +1 more source

Validation and standardization of designed N gene primer-based RT-PCR protocol for detecting Peste des Petits Ruminants virus in goats

Journal of Advanced Biotechnology and Experimental Therapeutics, 2022
The Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) test is one of the most popular and specific diagnostic tests to easily recognize the Peste des Petits Ruminants virus (PPRV) genome in clinical samples.
Sajeda Sultana, Munmun Pervin, Nazneen Sultana, Md. Rafiqul Islam, Mohammad Abu Hadi Noor Ali Khan   +4 more
doaj   +1 more source

Peste des Petits Ruminants Virus Exhibits Cell-Dependent Interferon Active Response

Frontiers in Cellular and Infection Microbiology, 2022
Peste des petits ruminants (PPR) is an acute and highly pathogenic infectious disease caused by peste des petits ruminants virus (PPRV), which can infect goats and sheep and poses a major threat to the small ruminants industry. The innate immune response
Jingyu Tang, Aoxing Tang, Hanyu Du, Nannan Jia, Jie Zhu, Chuanfeng Li, Chunchun Meng, Guangqing Liu   +7 more
doaj   +1 more source

Analysing Spatiotemporal Characteristics and Estimating the Spatial Distribution of Peste des Petits Ruminants (PPR) in Africa. [PDF]

Transbound Emerg Dis
Peste des petits ruminants (PPR) is a highly contagious disease that primarily affects small ruminants such as sheep and goats. Since first emerging in Africa, it has rapidly spread throughout the continent, causing significant mortality and posing a serious threat to livestock production and food security. In this study, we integrated diverse datasets
Chai R, Zhang S, Joka DL.
europepmc   +2 more sources

Growth Arrest and DNA Damage Protein 45A Promotes PPRV Replication via the Downregulation of TBK1 Expression to Inhibit IFN-β Signaling Pathway. [PDF]

FASEB J
A working model of host protein GADD45A regulation of PPRV replication. During PPRV infection, the viral protein V forms a complex with GADD45A in the cytoplasm. GADD45A interacts with TBK1 and inhibits its expression. Similarly, V also interacts with TBK1 and inhibits TBK1 expression.
Ding H, Yang W, Wu J, Wu J, Wang M, He J, Yuan L, Zheng H, Shang Y, Li D.   +9 more
europepmc   +2 more sources

Extracellular vesicles derived from PPRV-infected cells enhance signaling lymphocyte activation molecular (SLAM) receptor expression and facilitate virus infection.

PLoS Pathogens, 2022
Peste des petits ruminants virus (PPRV) is an important pathogen that seriously influences the productivity of small ruminants worldwide. PPRV is lymphotropic in nature and SLAM was identified as the primary receptor for PPRV and other Morbilliviruses ...
Yan Chen, Ting Wang, Yang Yang, Yuan Fang, Bao Zhao, Wei Zeng, Daiyue Lv, Leyan Zhang, Yanming Zhang, Qinghong Xue, Xiwen Chen, Jingyu Wang, Xuefeng Qi   +12 more
doaj   +1 more source

An Integrated Ecological Niche Modelling Framework for Risk Mapping of Peste des Petits Ruminants Virus Exposure in African Buffalo (Syncerus caffer) in the Greater Serengeti-Mara Ecosystem

Pathogens, 2023
Peste des petits ruminants (PPR) is a highly contagious viral disease of small ruminants that threatens livelihoods and food security in developing countries and, in some cases, wild ungulate species conservation.
Laura Carrera-Faja, Chris Yesson, Bryony A. Jones, Camilla T. O. Benfield, Richard A. Kock   +4 more
doaj   +1 more source

Self-assembly and release of peste des petits ruminants virus-like particles in an insect cell-baculovirus system and their immunogenicity in mice and goats. [PDF]

PLoS ONE, 2014
Peste des petits ruminants (PPR) is an acute, febrile, viral disease of small ruminants that has a significant economic impact. For many viral diseases, vaccination with virus-like particles (VLPs) has shown considerable promise as a prophylactic ...
Wenchao Li, Hongyan Jin, Xiukun Sui, Zhanzhong Zhao, Chenghuai Yang, Wenquan Wang, Junping Li, Gang Li   +7 more
doaj   +1 more source

Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses

Frontiers in Immunology, 2018
Peste des Petits Ruminants Virus (PPRV) is an extremely infective morbillivirus that primarily affects goats and sheep. In underdeveloped countries where livestock are the main economical resource, PPRV causes considerable economic losses.
Francesca Macchi, José Manuel Rojas, Andrea Elizabeth Verna, Noemí Sevilla, Valentina Franceschi, Giulia Tebaldi, Sandro Cavirani, Verónica Martín, Gaetano Donofrio   +8 more
doaj   +1 more source

Toll-like receptor responses to Peste des petits ruminants virus in goats and water buffalo. [PDF]

PLoS ONE, 2014
Ovine rinderpest or goat plague is an economically important and contagious viral disease of sheep and goats, caused by the Peste des petits ruminants virus (PPRV).
Sakthivel Dhanasekaran, Moanaro Biswas, Ambothi R Vignesh, R Ramya, Gopal Dhinakar Raj, Krishnaswamy G Tirumurugaan, Angamuthu Raja, Ranjit S Kataria, Satya Parida, Subbiah Elankumaran   +9 more
doaj   +1 more source