Results 1 to 10 of about 1,328 (105)

Genetic analyses and functional validation of ruminant SLAMs reveal potential hosts for PPRV [PDF]

Veterinary Research
Peste des petits ruminants (PPR), caused by the peste des petits ruminants virus (PPRV), is a highly contagious disease affecting ruminants. While goats and sheep are well-known hosts, PPRV has also spread to wild ruminants, and it remains unclear which ...
Haijin Liu, Yang Zengqi, Liu Haijin
exaly   +3 more sources

Immunization With Bovine Herpesvirus-4-Based Vector Delivering PPRV-H Protein Protects Sheep From PPRV Challenge

Frontiers in Immunology, 2021
The Morbillivirus peste des petits ruminants virus (PPRV) is the causal agent of a highly contagious disease that mostly affects sheep and goats and produces considerable losses in developing countries.
Daniel Rodríguez-Martín, JOSÉ M Rojas, Francesca Macchi   +2 more
exaly   +3 more sources

A Mouse Model of PPRV Infection for Elucidating Protective and Pathological Roles of Immune Cells

Frontiers in Immunology, 2021
The study was aimed at developing an accessible laboratory animal model to elucidate protective and pathological roles of immune mediators during Peste des petits ruminants virus (PPRV) infection.
Dhanavelu Muthuchelvan, Rajeev Kaul, Sharvan Sehrawat   +2 more
exaly   +3 more sources

MicroRNA-1 Negatively Regulates Peripheral NK Cell Function via Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Signaling Pathways During PPRV Infection

Frontiers in Immunology, 2020
Peste des petits ruminants virus (PPRV) has emerged as a significant threat to the productivity of small ruminants worldwide. PPRV is lymphotropic in nature and induces in the hosts a transient but severe immunosuppression, especially innate immunity ...
Xuefeng Qi, Yanming Zhang, Jingyu Wang   +2 more
exaly   +3 more sources

Establishment of a blocking enzyme-linked immunosorbent assay based on tandem expression of dominant antigenic epitopes of the nucleocapsid protein from attenuated and virulent peste des petits ruminants virus [PDF]

Frontiers in Cellular and Infection Microbiology
Peste des petits ruminants (PPR) is an acute, contagious disease caused by the Peste des Petits Ruminants virus (PPRV), mainly affecting small ruminants such as goats and sheep.
Kaiyu Zhu, Xiaolong Gao, Lina Tong, Xinchao Du, Yun Chen, Jinxin Xie, Shanhui Ren   +6 more
doaj   +2 more sources

Peste des petits ruminants virus (PPRV) modulates caprine dendritic cell function and induces immunosuppression through IL-10 upregulation [PDF]

Virulence
Peste des petits ruminants (PPR) is a WOAH notifiable disease affecting sheep and goats, caused by Peste des petits ruminants virus (PPRV), a morbillivirus of the Paramyxoviridae family. Infection with PPRV leads to immunosuppression, creating conditions
Pablo Nogales-Altozano, Abel Martínez-Rodrigo, José M Rojas, Noemí Sevilla   +3 more
doaj   +2 more sources

Ginsenoside Rb3 Suppresses Peste des Petits Ruminants Virus Replication by Inhibiting Autophagy to Potentiate Immune Responses [PDF]

Microorganisms
Peste des Petits Ruminants (PPR), a highly contagious disease of domestic and wild small ruminants, is characterized by severe morbidity and mortality. PPRV, the causative agent, is a morbillivirus in the family Paramyxoviridae.
Qinglu Zhao, Hongmei Chen, Zhanying Hu, Dingcheng Wei, Xueliang Zhu, Rui Zhang   +5 more
doaj   +2 more sources

Ginsenoside Rh1 suppresses Peste des petits ruminants virus replication by inhibiting autophagy to promote interferon responses and restrict inflammatory responses [PDF]

Frontiers in Veterinary Science
Peste des Petits Ruminants (PPR), a highly contagious disease of domestic and wild small ruminants, is characterized by severe morbidity and mortality. PPRV, the causative agent, is a morbillivirus in the family Paramyxoviridae.
Qinglu Zhao, Hongmei Chen, Dingcheng Wei, Zhanying Hu, Xueliang Zhu, Rui Zhang   +5 more
doaj   +2 more sources

Genomic characterization and evolution analysis of peste des petits ruminants virus in China from 2007 to 2024 [PDF]

Frontiers in Microbiology
Peste des petits ruminants (PPR) is a highly contagious and lethal disease, primarily affecting sheep, goats, and wild small ruminants. Genomic characterization and evolutionary analysis of the circulating PPR virus (PPRV) strains can provide valuable ...
Jingyue Bao, Ruiying Jiang, Ruiying Jiang, Shujuan Wang, Qinghua Wang, Jiao Xu, Yunling Zhao, Yutian Liu, Lin Li, Xiaohua Wang, Zhiliang Wang   +10 more
doaj   +2 more sources

The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication [PDF]

mBio
Peste des petits ruminants virus (PPRV) is an important pathogen that has long been a significant threat to small ruminant productivity worldwide. Iron metabolism is vital to the host and the pathogen.
Bo Wen, Wenchi Chang, Lulu Yang, Daiyue Lv, Lizhen Wang, Lei Wang, Yanzhao Xu, Jianhe Hu, Ke Ding, Qinghong Xue, Xuefeng Qi, Bo Yang, Jingyu Wang   +12 more
doaj   +2 more sources