Results 31 to 40 of about 330 (115)

MicroRNA-218 Regulates Signaling Lymphocyte Activation Molecular (SLAM) Mediated Peste des Petits Ruminants Virus Infectivity in Goat Peripheral Blood Mononuclear Cells

Frontiers in Immunology, 2019
Peste des petits ruminants virus (PPRV) has emerged as a significant threat to the productivity of small ruminants worldwide. SLAM was identified as the primary receptor for PPRV and other Morbilliviruses, although the regulation of SLAM expression is ...
Xuefeng Qi, Ting Wang, Zhen Li, Yangli Wan, Bo Yang, Wei Zeng, Yanming Zhang, Jingyu Wang   +7 more
doaj   +1 more source

Future research to underpin successful peste des petits ruminants virus (PPRV) eradication [PDF]

Journal of General Virology, 2017
Peste des petits ruminants virus (PPRV) is a significant pathogen of small ruminants and is prevalent in much of Africa, the Near and Middle East and Asia. Despite the availability of an efficacious and cheap live-attenuated vaccine, the virus has continued to spread, with its range stretching from Morocco in the west to China and Mongolia in the east.
Baron, Michael D., Diop, Bouna, Njeumi, Felix, Willett, Brian J., Bailey, Dalan   +4 more
openaire   +2 more sources

Mixed infection of peste-des-petits ruminants and Capripox in goats in South Kivu, Democratic Republic of Congo

Journal of Advanced Veterinary and Animal Research, 2017
Objective: We aimed at determining the prevalence and characterizing the CaPV, determining the CaPV-PPRV coinfection prevalence and providing data about phylogenetic relationship between the fusion protein of PPRV and P32 gene of CaPV.
Bwihangane Ahadi Birindwa, Gitao Chege George, Bisimwa Patrick Ntagereka, Okafor Christopher, Bebora Caroline Lilly   +4 more
doaj   +1 more source

Vaccination with recombinant adenoviruses expressing the peste des petits ruminants virus F or H proteins overcomes viral immunosuppression and induces protective immunity against PPRV challenge in sheep. [PDF]

PLoS ONE, 2014
Peste des petits ruminants (PPR) is a highly contagious disease of small ruminants caused by the Morbillivirus peste des petits ruminants virus (PPRV). Two recombinant replication-defective human adenoviruses serotype 5 (Ad5) expressing either the highly
José M Rojas, Héctor Moreno, Félix Valcárcel, Lourdes Peña, Noemí Sevilla, Verónica Martín   +5 more
doaj   +1 more source

Control of the induction of type I interferon by Peste des petits ruminants virus. [PDF]

PLoS ONE, 2017
Peste des petits ruminants virus (PPRV) is a morbillivirus that produces clinical disease in goats and sheep. We have studied the induction of interferon-β (IFN-β) following infection of cultured cells with wild-type and vaccine strains of PPRV, and the ...
Beatriz Sanz Bernardo, Stephen Goodbourn, Michael D Baron   +2 more
doaj   +1 more source

Neglected Hosts of Small Ruminant Morbillivirus

Emerging Infectious Diseases, 2018
Eradication of small ruminant morbillivirus (PPRV) is targeted for 2030. PPRV lineage IV is found in much of Asia and Africa. We used PPRV lineage IV strain Kurdistan/2011 in transmission trials to investigate the role of pigs, wild boar, and small ...
Claudia Schulz, Christine Fast, Kore Schlottau, Bernd Hoffmann, Martin Beer   +4 more
doaj   +1 more source

Peste des Petits Ruminants Virus Infection at the Wildlife–Livestock Interface in the Greater Serengeti Ecosystem, 2015–2019

Viruses, 2021
Peste des petits ruminants (PPR) is a viral disease of goats and sheep that occurs in Africa, the Middle East and Asia with a severe impact on livelihoods and livestock trade. Many wild artiodactyls are susceptible to PPR virus (PPRV) infection, and some
Bryony A. Jones, Mana Mahapatra, Daniel Mdetele, Julius Keyyu, Francis Gakuya, Ernest Eblate, Isaac Lekolool, Campaign Limo, Josephine N. Ndiwa, Peter Hongo, Justin S. Wanda, Ligge Shilinde, Maulid Mdaki, Camilla Benfield, Krupali Parekh, Martin Mayora Neto, David Ndeereh, Gerald Misinzo, Mariam R. Makange, Alexandre Caron, Arnaud Bataille, Geneviève Libeau, Samia Guendouz, Emanuel S. Swai, Obed Nyasebwa, Stephen L. Koyie, Harry Oyas, Satya Parida, Richard Kock   +28 more
doaj   +1 more source

Free ISG15 Inhibits the Replication of Peste des Petits Ruminants Virus by Breaking the Interaction of Nucleoprotein and Phosphoprotein

Microbiology Spectrum, 2022
Peste des petits ruminants virus (PPRV) causes a highly contagious disease in small ruminants and severe economic losses in developing countries. PPRV infection can stimulate high levels of interferon (IFN) and many IFN-stimulated genes (ISGs), such as ...
Jingyu Tang, Aoxing Tang, Nannan Jia, Hanyu Du, Chuncao Liu, Jie Zhu, Chuanfeng Li, Chunchun Meng, Guangqing Liu   +8 more
doaj   +1 more source

Dysregulated miRNAome and Proteome of PPRV Infected Goat PBMCs Reveal a Coordinated Immune Response [PDF]

Frontiers in Immunology, 2018
In this study, the miRNAome and proteome of virulent Peste des petits ruminants virus (PPRV) infected goat peripheral blood mononuclear cells (PBMCs) were analyzed. The identified differentially expressed miRNAs (DEmiRNAs) were found to govern genes that modulate immune response based on the proteome data.
Alok Khanduri, Amit Ranjan Sahu, Amit Ranjan Sahu, Sajad Ahmad Wani, Sajad Ahmad Wani, Raja Ishaq Nabi Khan, Aruna Pandey, Shikha Saxena, Waseem Akram Malla, Piyali Mondal, Kaushal Kishor Rajak, D. Muthuchelvan, Bina Mishra, Aditya P. Sahoo, Yash Pal Singh, Raj Kumar Singh, Ravi Kumar Gandham, Ravi Kumar Gandham, Bishnu Prasad Mishra   +18 more
openaire   +3 more sources

Systems Biology behind Immunoprotection of Both Sheep and Goats after Sungri/96 PPRV Vaccination

mSystems, 2021
Peste des petits ruminants (PPR) by PPR virus (PPRV) is an World Organisation for Animal Health (OIE)-listed acute, contagious transboundary viral disease of small ruminants. The attenuated Sungri/96 PPRV vaccine used all over India against this PPR provides long-lasting robust innate and adaptive immune response.
Sajad Ahmad Wani, Manas Ranjan Praharaj, Amit R. Sahu, Raja Ishaq Nabi Khan, Shikha Saxena, Kaushal Kishor Rajak, Dhanavelu Muthuchelvan, Aditya Sahoo, Bina Mishra, Raj Kumar Singh, Bishnu Prasad Mishra, Ravi Kumar Gandham   +11 more
openaire   +4 more sources