Results 41 to 50 of about 3,280 (219)

Two replication-defective adenoviral vaccine vectors for the induction of immune responses to PPRV [PDF]

Vaccine, 2013
Peste des petits ruminants is a highly contagious disease of small ruminants caused by a Morbillivirus, peste des petits ruminants virus (PPRV). Two recombinant replication-defective human adenovirus serotype 5 (Ad5) containing the highly immunogenic fusion protein (F) and hemaglutinine protein (H) genes from PPRV were constructed.
José M. Rojas, Héctor Moreno, A. J. García, Juan Camilo Ramírez, Noemı́ Sevilla, Verónica Martı́n   +5 more
openalex   +5 more sources

Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96 [PDF]

Journal of Virology, 2018
Despite the widespread use of live attenuated PPRV vaccines, this is the first systematic analysis of the immune response elicited in small ruminants. These data will help in the establishment of the immunological determinants of protection, an important step in the development of new vaccines, especially DIVA vaccines using alternative vaccination ...
Hodgson, Sophia, Moffat, Katy, Hill, Holly, Flannery, John T., Graham, Simon, Baron, Michael D., Darpel, Karin E.   +6 more
openaire   +4 more sources

Extracellular vesicles derived from PPRV-infected cells enhance signaling lymphocyte activation molecular (SLAM) receptor expression and facilitate virus infection.

PLoS Pathogens, 2022
Peste des petits ruminants virus (PPRV) is an important pathogen that seriously influences the productivity of small ruminants worldwide. PPRV is lymphotropic in nature and SLAM was identified as the primary receptor for PPRV and other Morbilliviruses ...
Yan Chen, Ting Wang, Yang Yang, Yuan Fang, Bao Zhao, Wei Zeng, Daiyue Lv, Leyan Zhang, Yanming Zhang, Qinghong Xue, Xiwen Chen, Jingyu Wang, Xuefeng Qi   +12 more
doaj   +1 more source

Self-assembly and release of peste des petits ruminants virus-like particles in an insect cell-baculovirus system and their immunogenicity in mice and goats. [PDF]

PLoS ONE, 2014
Peste des petits ruminants (PPR) is an acute, febrile, viral disease of small ruminants that has a significant economic impact. For many viral diseases, vaccination with virus-like particles (VLPs) has shown considerable promise as a prophylactic ...
Wenchao Li, Hongyan Jin, Xiukun Sui, Zhanzhong Zhao, Chenghuai Yang, Wenquan Wang, Junping Li, Gang Li   +7 more
doaj   +1 more source

Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses

Frontiers in Immunology, 2018
Peste des Petits Ruminants Virus (PPRV) is an extremely infective morbillivirus that primarily affects goats and sheep. In underdeveloped countries where livestock are the main economical resource, PPRV causes considerable economic losses.
Francesca Macchi, José Manuel Rojas, Andrea Elizabeth Verna, Noemí Sevilla, Valentina Franceschi, Giulia Tebaldi, Sandro Cavirani, Verónica Martín, Gaetano Donofrio   +8 more
doaj   +1 more source

Development of an Enzyme-Linked Immunosorbent Assay Based on CD150/SLAM for the Detection of Peste des Petits Ruminant Virus

Frontiers in Veterinary Science, 2020
Peste des petits ruminant (PPR) is an economically important severe viral disease of small ruminants that affects primarily the respiratory and digestive tract.
Meera Prajapati, Meera Prajapati, Meera Prajapati, Yongxi Dou, Xueliang Zhu, Shuaiyang Zhao, Niyokwishimira Alfred, Yanmin Li, Zhidong Zhang, Zhidong Zhang   +9 more
doaj   +1 more source

A dynamic model of transmission and elimination of peste des petits ruminants in Ethiopia [PDF]

, 2018
Peste des petits ruminants (PPR), a devastating viral disease of sheep and goats, has been targeted by the global community for eradication within the next 15 years.
Abebe, Agnès Waret-Szkuta, Anton Camacho, Baars, Baudon, Beyene, Dean, Dirk U. Pfeiffer, Faris, François Roger, Getachew, Gubbins, Guillaume Fournié, Hammami, Hoffmann, Intisar, Jones, Kardjadj, Kihu, Kivaria, Kullback, Laike M. Yigezu, Libeau, Marashi, Mariner, Megersa, Molia, Muniraju, Mweu, Ortiz-Pelaez, Pegram, Roger, Rony, Taye, Waret-Szkuta   +34 more
core   +5 more sources

Toll-like receptor responses to Peste des petits ruminants virus in goats and water buffalo. [PDF]

PLoS ONE, 2014
Ovine rinderpest or goat plague is an economically important and contagious viral disease of sheep and goats, caused by the Peste des petits ruminants virus (PPRV).
Sakthivel Dhanasekaran, Moanaro Biswas, Ambothi R Vignesh, R Ramya, Gopal Dhinakar Raj, Krishnaswamy G Tirumurugaan, Angamuthu Raja, Ranjit S Kataria, Satya Parida, Subbiah Elankumaran   +9 more
doaj   +1 more source

MicroRNA-218 Regulates Signaling Lymphocyte Activation Molecular (SLAM) Mediated Peste des Petits Ruminants Virus Infectivity in Goat Peripheral Blood Mononuclear Cells

Frontiers in Immunology, 2019
Peste des petits ruminants virus (PPRV) has emerged as a significant threat to the productivity of small ruminants worldwide. SLAM was identified as the primary receptor for PPRV and other Morbilliviruses, although the regulation of SLAM expression is ...
Xuefeng Qi, Ting Wang, Zhen Li, Yangli Wan, Bo Yang, Wei Zeng, Yanming Zhang, Jingyu Wang   +7 more
doaj   +1 more source

An Integrated Ecological Niche Modelling Framework for Risk Mapping of Peste des Petits Ruminants Virus Exposure in African Buffalo (Syncerus caffer) in the Greater Serengeti-Mara Ecosystem

Pathogens, 2023
Peste des petits ruminants (PPR) is a highly contagious viral disease of small ruminants that threatens livelihoods and food security in developing countries and, in some cases, wild ungulate species conservation.
Laura Carrera-Faja, Chris Yesson, Bryony A. Jones, Camilla T. O. Benfield, Richard A. Kock   +4 more
doaj   +1 more source