Results 41 to 50 of about 1,678,179 (242)
Revue Nature et Technologie, 2023 L’analyse statistique est devenue un outil indispensable d'aide à la décision en matière de bonne gestion des ressources en eaux, De ce fait, une analyse statistique des débits maximaux annuels a été réalisée dans le bassin-versant moyen et le bas de ...
Brahim HABIBI, Mohamed MEDDI
doaj +6 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Temporal structures for Fast and Slow Speech Rate [PDF]
, 1998 The rhythmic component in speech synthesis often remains rather rudimentary, despite recent major efforts in the modeling of prosodic models. The European COST Action 258 has identified this problem as one of the next challenges for speech synthesis ...
Zellner, Brigitte
core +2 more sources
Consommation de psychotropes et délinquance : de bons prédicteurs de l’abandon scolaire ? [PDF]
, 1998 Although empirical links between deviant behavior and school dropout have been extensively demonstrated, the specific influence of drug use and delinquency on school dropout is still not clear and varies across studies.
Boulerice, Bernard +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
INRAE Productions Animales, 1992 Les différentes méthodes de prédiction des quantités ingérées peuvent être regroupées en 3 grands types : 1) les équations de régression multiple, généralement empiriques et issues de compilation de données expérimentales, 2) le système de 2 prédictions,
P. FAVERDIN
doaj +1 more source
Prédiction de mots et saisie de requêtes sur interfaces limitées : dispositifs mobiles et aide au handicap [PDF]
, 2011 chapitre 10Ce chapitre fait le tour de la question des techniques de prédiction lexicale utilisées aussi bien dans les systèmes d'aide à la communication pour personnes handicapées que dans les systèmes d'aide à la saisie de texte sur dispositifs limités
Antoine, Jean-Yves
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source