Results 51 to 60 of about 1,678,179 (242)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Occupational Health Problem Network : the Exposome
We present a thinking on the concept of relational networks applied to the french national occupational disease surveillance and prevention network (R\'eseau National de Vigilance et de Pr\'evention des Pathologies Professionnelles, RNV3P). This approach
Bicout, Dominique J +2 more
core +1 more source
A probabilistic high cycle fatigue model applied to cast Al-Si alloys [PDF]
In this work, the high cycle fatigue behavior of cast hypo-eutectic Al-Si alloys is investigated. It is observed that two different coexisting fatigue initiation mechanisms can occur in these materials depending on the presence of different ...
AUGUSTINS, Louis +3 more
core +3 more sources
Rôle de l’autodétermination et des aptitudes scolaires dans la prédiction des absences scolaires et l’intention de décrocher [PDF]
Le but de l’étude était d’examiner l’importance relative de la motivation autodéterminée et des aptitudes scolaires dans la prédiction des absences scolaires et de l’intention d’abandonner les études.
Blanchard, Céline +3 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
La conservation et la bonne gestion des espèces forestières menacées de dégradation, impose la connaissance de leurs aires de distribution potentielle et des facteurs environnementaux conditionnant leur répartition.
Nabil RIFAI +5 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mise au point d'outils portables de spectrométrie dans le proche infrarouge (SPIR) pour évaluer la qualité des fourrages à la ferme [PDF]
L'évaluation de la qualité nutritive des ressources fourragères ainsi que leur variation saisonnière sont indispensables pour la gestion raisonnée de l'alimentation des ruminants.
Barbet-Massin, Vladimir +8 more
core

