Results 171 to 180 of about 2,255,048 (250)

Le collectif Pasde0deconduite et la lutte contre l’approche prédictive de prévention de la délinquance en France : Entrevue avec Christine Bellas-Cabane, cofondatrice du Collectif et co-initiatrice de l’appel en réponse à l’expertise INSERM [PDF]

, 2007
Larouche, Annie
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Implementing cancer prevention in occupational healthcare: initial insights from occupational healthcare staff in Central and Southern Europe - findings from the CPW project. [PDF]

BMC Cancer
Roth C, Kostrzewa M, Collatuzzo G, Biagioli V, Seyyedsalehi MS, Giordani S, Godono A, Otelea MR, Mates D, Popescu FG, Tardon A, Fernandez-Tardon G, Rodriguez-Suarez MM, Fabiánová E, Bérešová J, Klöslová Z, Blažinová MK, Ďurajová V, Crull I, Schneider-Kamp A, Boffetta P, Wensing M.   +21 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Report from the WPA Section on Suicidology: recent advances and activities. [PDF]

World Psychiatry
Carli V, Sutori S, Iosue M.
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A Prevention-Focused Geospatial Epidemiology Framework for Identifying Multilevel Vulnerability Across Diverse Settings. [PDF]

Healthcare (Basel)
Jean-Baptiste CO.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Sustaining Recovery After Low-Intensity Treatment for Anxiety and Depression in NHS Talking Therapies: A Multiphase Participatory and Consensus-Building Study of Stakeholder Priorities and Recommendations. [PDF]

Depress Anxiety
Nawaz S, Bee P, Faija C.
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source