Results 81 to 90 of about 2,428,341 (233)
Criminologie, 2018 Chaque année, dans le monde, entre 48 et 50 millions de personnes se retrouvent endeuillées à la suite d’un suicide. Au Canada seulement, ce sont 4 000 individus qui se suicident chaque année, laissant derrière eux un grand nombre de personnes qui ...
Rae Spiwak, Ph. D. +4 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Le tourisme sexuel en Thaïlande : une prostitution entre misère et mondialisation
Téoros, 2003 Près de neuf millions de touristes ont visité la Thaïlande en l’an 2000, parmi lesquels 65 à 70 % sont des hommes. Malgré d’intenses campagnes médiatiques de sensibilisation contre le tourisme sexuel et nombre de batailles judiciaires à l’encontre des ...
Franck Michel
doaj
Le défi du traitement et de la prévention des troubles concomitants sur la base de données probantes
Criminologie, 2009 RésuméAu cours des vingt dernières années, au Canada et aux États-Unis, la forte prévalence des troubles concomitants de santé mentale et de toxicomanie a suscité un intérêt accru, tout spécialement à l’égard des traitements.
Michel Perreault +3 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Regard éthique et critique sur la seconde édition du Sommet de la santé durable
Canadian Journal of BioethicsLes 30 et 31 janvier 2024, la seconde édition du Sommet de la santé durable, organisée par l’Association pour la santé publique du Québec, a eu lieu, et ce, simultanément à Québec et à Montréal.
Valérie Lafond +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source