Results 61 to 70 of about 4,139,485 (271)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Визуальная идентификация общественного объединения профессиональных коммуникаторов на примере клуба пресс-служб Челябинской Области

open access: yesДинамика медиасистем
Уникальное общественное объединение, созданное для профессионального развития PR-специалистов – Клуб пресс-служб Челябинской области – за 16-летнюю историю существования пришел к необходимости выхода на новый уровень.
Анастасия Гусенкова
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Genre PRology and convergence of genres of PR text [PDF]

open access: yesЖанры речи
In the basis of a special area of genre PRology as a branch of the science of public relations the authors put the criterion of the diversity of PR-information in multi-channel public communication via new media.
Stepanov, Valentin Nikolaevich   +1 more
doaj   +1 more source

Anisotropic phonon conduction and lattice distortions in CMR-type bilayer manganite (La$_{1-z}$Pr$_{z}$)$_{1.2}$Sr$_{1.8}$Mn$_{2}$O$_{7}$ (z=0,0.2,0.4 and 0.6) single crystals [PDF]

open access: yes, 2003
We have undertaken a systematic study of thermal conductivity as a function of temperature and magnetic field of single crystals of the compound (La$_{1-z}$Pr$_{z}$)$_{1.2}$Sr$_{1.8}$Mn$_{2}$O$_{7}$ for $z$(Pr) =0.2,0.4. and 0.6.
A. Revcolevschi   +31 more
core   +5 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Hearing loss, tinnitus, hyperacusis, and diplacusis in professional musicians: a systematic review [PDF]

open access: yes, 2018
Professional musicians (PMs) are at high risk of developing hearing loss (HL) and other audiological symptoms such as tinnitus, hyperacusis, and diplacusis.
de Vincentiis, Marco   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Researches on the Correlation Between Estrogen and Progesterone Receptors Expression and Disease-Free Survival of Endometrial Cancer

open access: yesCancer Management and Research, 2020
Siling Ren,1,* Jingxian Wu,2,* Wanchun Yin,1 Qianqian Liao,1 Sailan Gong,1 Beibei Xuan,1 Xiaoling Mu1 1Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China ...
Ren S   +6 more
doaj  

Scaling in thermal convection: A unifying theory [PDF]

open access: yes, 1999
A systematic theory for the scaling of the Nusselt number $Nu$ and of the Reynolds number $Re$ in strong Rayleigh-Benard convection is suggested and shown to be compatible with recent experiments. It assumes a coherent large scale convection roll (``wind
Grossmann, Siegfried, Lohse, Detlef
core   +3 more sources

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