Results 81 to 90 of about 987,544 (291)

A pharmacokinetic study of radiprodil oral suspension in healthy adults comparing conventional venous blood sampling with two microsampling techniques

Pharmacology Research & Perspectives, 2019
In this phase I, single‐center, open‐label study of ten heathy adults (18‐45 years; NCT02647697), the PK, safety, and tolerability profile of radiprodil oral suspension in healthy adults were assessed, as well as two PK microsampling techniques.
David Sciberras, Christian Otoul, Françoise Lurquin, John Smeraglia, Aurélia Lappert, Steven De Bruyn, Jan Jaap van Lier   +6 more
doaj   +1 more source

Pra-Pemuridan

, 2020
Tema utama dalam Alkitab dari Kitab Kejadian sampai Kitab Wahyu ialah tema pendamaian, yaitu memulihkan hubungan manusia dengan Allah. Oleh sebab itu, Yesus memulai suatu gerakan yang telah mengubah dunia dengan melahirkan 12 murid untuk mengubah dunia secara total.
openaire   +2 more sources

Meyniel's conjecture holds for random graphs [PDF]

, 2014
In the game of cops and robber, the cops try to capture a robber moving on the vertices of the graph. The minimum number of cops required to win on a given graph $G$ is called the cop number of $G$.
Lat, Nicholas Wormald, Pawe L Pra
core  

Long‐term trends in parasite diversity and infection levels: approaches and patterns

Biological Reviews, EarlyView.
ABSTRACT Parasites exist in every ecosystem, affecting nearly all organisms and playing a complex role in human societies. On the one hand, they contribute substantially to biodiversity and support ecosystem stability by performing essential ecological functions.
Cyril Hammoud, Juan Antonio Balbuena, Isabel Blasco‐Costa, Katie O'Dwyer, Rachel A. Paterson, Tomáš Scholz, Christian Selbach, Bernd Sures, David W. Thieltges   +8 more
wiley   +1 more source

The role of disorder in the dynamics of critical fluctuations of mean field models

, 2011
The purpose of this paper is to analyze how the disorder affects the dynamics of critical fluctuations for two different types of interacting particle system: the Curie-Weiss and Kuramoto model.
Collet, Francesca, Pra, Paolo Dai
core   +1 more source

Shaping research in marine functional connectivity for integrated and effective marine science and management

Biological Reviews, EarlyView.
ABSTRACT Effective knowledge of ecological connectivity at sea and at the land–sea interface is key to supporting global policy goals to conserve and restore ocean biodiversity and function. However, a persistent lack of commonality in terminology and understanding around the concept of connectivity in marine ecological studies hampers its integration ...
Audrey M. Darnaude, Susanne E. Tanner, Andreu Blanco, Anna M. Sturrock, Yael Teff Seker, Angel Pérez‐Ruzafa, Jonne Kotta, Tamar Guy‐Haim, Francisco R. Barboza, Manuel Hidalgo, Katell Guizien, Jerneja Penca, Lucía López‐López, Maria Beger, Federica Costantini, Sophie Arnaud‐Haond, Cynthia Riginos, Kris Hostens, Gil Rilov, Stelios Katsanevakis, Ewan Hunter   +20 more
wiley   +1 more source

Intranasal Pharmacokinetics of Morphine ARER, a Novel Abuse-Deterrent Formulation: Results from a Randomized, Double-Blind, Four-Way Crossover Study in Nondependent, Opioid-Experienced Subjects

Pain Research and Management, 2018
Objective. To investigate the pharmacokinetics (PK) of Morphine ARER, an extended-release (ER), abuse-deterrent formulation of morphine sulfate after oral and intranasal administration. Methods.
Lynn R. Webster, Carmela Pantaleon, Matthew Iverson, Michael D. Smith, Eric R. Kinzler, Stefan Aigner   +5 more
doaj   +1 more source

Meaningful engagement of people living with HIV who use drugs: methodology for the design of a Peer Research Associate (PRA) hiring model

Harm Reduction Journal, 2016
BackgroundCommunity-based HIV, harm reduction, and addiction research increasingly involve members of affected communities as Peer Research Associates (PRAs)—individuals with common experiences to the participant population (e.g.
K. Closson, R. McNeil, P. McDougall, S. Fernando, A. Collins, R. Baltzer Turje, T. Howard, S. Parashar   +7 more
semanticscholar   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

Biological Reviews, EarlyView.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman, Daphne Cortese, Amelia Munson, Jan Lindström, Shaun S. Killen   +4 more
wiley   +1 more source

Advances in Parahydrogen‐Induced Polarization for Nuclear Magnetic Resonance of Peptides, Proteins, and Biopolymers

ChemistryEurope, EarlyView.
Hyperpolarization by parahydrogen‐induced polarization enhances the sensitivity of nuclear magnetic resonance spectroscopy of amino acids, peptides, mini‐proteins, and biopolymers using nonnatural amino acids with unsaturated side chains up to three orders of magnitude.
Gerd Buntkowsky
wiley   +1 more source