Results 111 to 120 of about 55,271,543 (296)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Re-addressing the role of knitted textile design knowledge: auxetic textiles from a practice-led, designer-maker perspective [PDF]

open access: yes, 2014
This study reacts to the segregation of knowledge and practice surrounding weft-knitted textiles, their design and applications. This study challenges current disciplinary practices that divide knit into scientific, design and art areas by describing a ...
Glazzard, M
core  

Clouds Running Out of Juice: A Special Podcast Episode Featuring Tim Winton’s Climate Fiction

open access: yesAustralian Journal of Environmental Education
This paper presents a pedagogical experiment in the form of a fictional podcast episode that “aired” in January 2025, featuring Tim Winton’s climate fiction novel Juice (2024).
Rumen Rachev, Jo Pollitt, Emma Nicoletti
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Practice Research Partnerships in Social Work:Addressing Impact and Credible Evidence [PDF]

open access: yes
Purpose: This article builds on the Practice Research Collaboratives (PRCs) as an initiative that developed from the Fifth Conference on Practice Research to provide a platform for practice researchers to engage actively around impact and influence ...
Fouché, Christa   +6 more
core   +1 more source

About The Night

open access: yesScreenworks
This project explores fiction filmmaking as practice-led research, examining innovative, inclusive storytelling while addressing barriers to creative freedom in production.
Lee-Jane Bennion-Nixon
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Journalism as research: Developing radio documentary theory from practice [PDF]

open access: yes, 2011
Journalism academics around the world face the challenge of having their journalism practice recognised as academic research. This dissertation presents a model of how journalism practitioner-academics can present their in-depth journalistic practice in ...
Lindgren, Mia
core  

Theory and Practice-led Research: Historically-based Research as a Springboard for Enquiry

open access: yesΔιεθνές Συνέδριο για την Ανοικτή & εξ Αποστάσεως Εκπαίδευση, 2016
<p>Σε ερευνητικό επίπεδο συχνά γίνεται διάκριση μεταξύ <em>θεωρίας</em> και <em>εφαρμογής</em> σε αυτό που ονομάζουμε τέχνη. Με τον διαχωρισμό που γίνεται μεταξύ <em>θεωρίας</em>, υπό τη έννοια του ‘κειμένου’, αφενός και <em>εφαρμογής</em>, υπό τη έννοια της ‘εικόνας – του εικαστικού έργου ...
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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