Results 121 to 130 of about 55,271,543 (296)

The metaphorical value of lace in contemporary art: the transformative process of a practice-led inquiry [PDF]

open access: yes, 2013
This thesis examines lace as a metaphor in contemporary art, comprising a practice-led inquiry based on the lace archive of Nottingham Trent University. Lace is placed in the context of creative art practice to establish an overview and understanding of ...
Buttress, J
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Practice-led research and the innovation agenda : beyond the postgraduate research degree in the arts, design and media [PDF]

open access: yes, 2009
The rise of the ‘practice-led’ research approach has given us a new way of understanding what creative practice in art, design and media can do in the academy and the world— it can materialise new ideas and forms into being as a form of experimental ...
Jaaniste, Luke O., Haseman, Bradley C.
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Supporting patient and public involvement in industry-led research: guidance for charities [PDF]

open access: yes, 2019
This guidance has been developed by the Charities Research Involvement Group in collaboration with the Health Research Charities Ireland. It aims to help charities in the UK and the Republic of Ireland to promote and support patient and public ...
Ratcliffe, Natasha   +9 more
core   +1 more source

Extinction studies in focus: Reflections on photography at a time of ecological decline

open access: yesCambridge Prisms: Extinction
Through compositional inclusion or exclusion, the photograph can assert and communicate what belongs in a picture, in a landscape, in an ecosystem. It can illuminate what we deem conservation-worthy, or, on a larger scale, which extinctions are attention-
Kate Simpson   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Illumination through illustration: Positioning illustration as practice-led research [PDF]

open access: yes
This thesis represents a practice-led enquiry into contemporary illustration from a UK perspective. This thesis argues for illustration to be recognised as an inductive practice-led research process, within both education and developing criticism.
Black, Stephanie
core  

The Role of Documentation in Practice-Led Research [PDF]

open access: yes, 2007
Practice-led research in the field of art and design usually involves a study of the interplay between a researcher-practitioner and her artistic work in process.
Nimkulrat, Nithikul   +1 more
core  

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