Results 81 to 90 of about 8,275,365 (298)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Política de Qualidade e Eficácia dos Cuidados de Saúde Rural
Revista Brasileira de Medicina de Família e Comunidade, 2013 A Política de Qualidade e Eficácia dos Cuidados de Saúde Rural foi desenvolvida pelo Grupo de Trabalho de Medicina Rural. O objetivo é fornecer uma estrutura que estimule o desenvolvimento de metas diretas e indiretas e de avaliações da qualidade e ...
Working Party on Rural Practice WONCA
doaj +1 more source
Lessons for research policy and practice: The case of co-enquiry research with rural communities [PDF]
, 2016 This article explores the relationship between institutional funding for research and community-based or co-enquiry research practice. It examines the implementation of co-enquiry research in the COMBIOSERVE project, which was funded by the European ...
Corbera Elizalde, Esteve +24 more
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Reflective Practice and Its Contributions to ACPE Flourishing
, 2022 The author recounts her own journey in ACPE and how Reflective Practice has enhanced her journey. She also sees how the material that is in the journal has also had a positive influence on ACPE as an organization as it has developed and ...
Freeman, Susan
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Revista Brasileira de Medicina de Família e Comunidade, 2013 Adotado na 5ª Conferência Mundial de Saúde Rural da Wonca Melbourne, Austrália, 3 de maio de ...
Working Party on Rural Practice WONCA
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source