Results 101 to 110 of about 6,492,501 (315)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
When Clinical Practice is Digital: Reflection of Supervision at VITAS Innovative Hospice Care
, 2012 VITAS Innovative Hospice Care is a model of distance accountability for clinical practice. Because all hospice staff in VITAS is supervised at a distance, digital communication is an essential part of clinical practice.
Rutland, Martha
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Gastroenterology Research and Practice, 2023 Gastroenterology Research and Practice
doaj +1 more source
Theological Reflective Practice: A Key Tool for Contemporary Ministry
, 2012 The pace of modern ministry often leaves little time or space to plan or assess strategies already in motion or stop long enough to consider the implication of our pastoral actions.
Sims, Neil
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Understanding the practice assessment document
, 2011 Chapter Aims The purpose of this chapter is to explore the practice assessment document and the meaning of learning outcomes in more depth. After reading this chapter you will be able to: - Explain the role of the practice assessment in the student's ...
Gasston-Hales, Melanie
core
, 2009 BACKGROUND: Previous studies of inter-practice variation of the prevalence of hypertension and diabetes mellitus showed wide variations between practices.
Markus MJ Nielen +8 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source