Results 71 to 80 of about 301,813 (312)

Care of Women with Breech or Previous Caesarean Birth- Evidence-based Best Practice Guideline

open access: yes, 2004
Member of the NZ Guidelines Group to develop a Ministry of Health Commissioned Guideline. This was a multidisciplinary group who worked for two years reviewing the evidence and preparing a summary and then developing the guideline.
Waller, N   +8 more
core  

Incorporating patient preferences in the management of multiple long-term conditions: is this a role for clinical practice guidelines?

open access: yes, 2015
Background: Clinical practice guidelines provide an evidence-based approach to managing single chronic conditions, but their applicability to multiple conditions has been actively debated.
Boyle, Frances M.   +7 more
core   +1 more source

Can't do it, won't do it! Developing a theoretically framed intervention to encourage better decontamination practice in Scottish dental practices [PDF]

open access: yes, 2009
Background: Guidance on the cleaning of dental instruments in primary care has recently been published. The aims of this study are to determine if the publication of the guidance document was enough to influence decontamination best practice and to ...
Ramsay, Craig R   +20 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Implementing evidence-based practice in primary care: perceptions of a multifaceted programme to encourage guideline use

open access: yes, 2002
Objective To explore the acceptability of the various elements of a multifaceted intervention designed to facilitate the process of guideline implementation by primary care teams and to understand constraints to the use of guidelines in this setting.
Kaba, Evridiki   +4 more
core  

Clinical practice guideline for the physiotherapy of patients with whiplash-associated disorders.

open access: yes, 2002
Item does not contain fulltextSTUDY DESIGN: A clinical practice guideline. OBJECTIVES: To assist physiotherapists in decision making and to improve the efficacy and uniformity of care for patients with whiplash-associated disorders Grades I and II ...
Hendriks, E.   +22 more
core   +1 more source

National stakeholders’ perceptions of the processes that inform the development of national clinical practice guidelines for primary healthcare in South Africa

open access: yesHealth Research Policy and Systems, 2018
Background There is increased international focus on improving the rigour of clinical practice guideline (CPG) development practices. However, few empirical studies on CPG development have been conducted in low- and middle-income countries.
Tamara Kredo   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Validation of a guideline-based composite outcome assessment tool for asthma control [PDF]

open access: yes, 2007
Background: A global definition of asthma control does not currently exist. The purpose of this study was to validate two new guideline-based composite measures of asthma control, defined as totally controlled (TC) asthma and well controlled (WC ...
Spencer, S   +13 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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