Results 111 to 120 of about 302,059 (306)

Public health grand rounds [PDF]

Have you ever wondered what kind of impact CDC science has? Did you ever want to know if your published research is likely to have impact on a significant health outcome?

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Updating the Iranian National Childbirth Preparation Classes guideline: a multi-phase mixed-methods protocol study

Reproductive Health
Background Childbirth Preparation Classes (CPCs) have been implemented nationally in Iran for more than two decades to promote maternal empowerment and physiological childbirth.
Mahla Shafeei, Talat Khadivzadeh, Monavar Afzal-Aghaei, Mohammad Ahmadian, Sedigheh Abdollahpour   +4 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The use of ciprofloxacin and fluconazole in Italian neonatal intensive care units: a nationwide survey

BMC Pediatrics, 2013
Background Treatment and prophylaxis of sepsis in very low birth weight neonates is a matter of concern and research is being undertaken with the aim to give rise to shared approaches based on solid evidence.
Pandolfini Chiara, Marco Sequi, Paolo Manzoni, Maurizio Bonati   +3 more
doaj   +1 more source

Malignant pleural mesothelioma: main topics of American Society of Clinical Oncology clinical practice guidelines for diagnosis and treatment

Journal of Thoracic Disease, 2018
Malignant pleural mesothelioma (MPM) is a rare, asbestos-related neoplasm with a poor prognosis. Men are more often affected than women and the incidence in males in the US is 1.5/100,000/year (according to data in the SEER database), in Turkey it is 2.88/100,000/year and in Great Britain it is 5.4/100,000/year (1,2).
Malgorzata, Szolkowska, Katarzyna, Blasinska-Przerwa, Magdalena, Knetki-Wroblewska, Piotr, Rudzinski, Renata, Langfort   +4 more
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Knowledge about the best practice guidelines in the nursing degree: A non‐randomized post‐test design

Nursing Open
Aim To compare knowledge of Nursing Degree students about Best Practice Guidelines when there are included as teaching content in a subject vs knowledge through having the usual internship experience without teaching specific guidelines contents.
Rosa García‐Sierra, María Isabel Fernández‐Cano, Miguel Jiménez‐Pera, Maria Feijoo‐Cid, Antonia Arreciado Marañón   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Adapting Guidelines for Emergencies in the Digital Age : Session 176, February 13, 2019 [PDF]

handout-176_V3_FINAL.pdf?_ga=2.210925200.487570670.1550516005-38364691 ...

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