Results 111 to 120 of about 451,692 (296)

Do Physicians Respond to Liability Standards? [PDF]

, 2015
In this paper, we explore the sensitivity in the clinical decisions of physicians to the standards of care expected of them under the law, drawing on the abandonment by states over time of rules holding physicians to standards determined by local customs
Frakes, Michael D., Frank, Matthew, Seabury, Seth   +2 more
core   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Assessing the landscape of family medicine in India: A focus on qualification and practice patterns

Journal of Family Medicine and Primary Care
Aims and Objectives: Describe the demographic and professional profiles of the family physicians. 1. To study the factors associated with practice patterns. Methodology: It is a cross-sectional, questionnaire-based study.
Hemavathi Dasappa, Mohan Kubendra, Namiya Jose, Resmi S. Kaimal, Vandana Boobna, S Ramya   +5 more
doaj   +1 more source

No. 55: The Engagement of the Zimbabwean Medical Diaspora [PDF]

, 2011
Despite the well-documented negative impacts of the ‘brain drain’ of health professionals from Africa, there is an argu­ment that their departure is not an absolute loss and that transnationally-oriented medical migrants (or diasporas) can act as ...
Chikanda, Abel
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Gender Perspectives on Self-Employment Among Israeli Family Physicians: A Qualitative Study

Social Sciences
Background: While previous studies have shown that occupational choices are influenced by traditional gender perceptions, little is known about gender’s role in choosing self-employment among family physicians.
Irit Chudner, Avi Shnider, Omer Gluzman, Hadas Keidar, Motti Haimi   +4 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Teaching physicians the GPGP method promotes deprescribing in both inpatient and outpatient settings

Therapeutic Advances in Drug Safety, 2019
Background In complex older patients, inappropriate medication use and polypharmacy (IMUP) are commonplace and increasing exponentially. Reducing IMUP is a challenge in multiple clinical contexts, including acute admission and family practice, due to ...
Aaron Jason Bilek, Yuval Levy, Haneen Kab, Pavel Andreev, Doron Garfinkel   +4 more
doaj   +1 more source