Results 91 to 100 of about 451,692 (296)

An integrative model of the management of hospital physician relationships [PDF]

open access: yes, 2010
Hospital Physician Relationships (HPRs) are of major importance to the health care sector. Drawing on agency theory and social exchange theory, we argue that both economic and noneconomic integration strategies are important to effective management of ...
Annemans, Lieven   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Expert Opinion Report on the Challenges in the Management of Psoriatic Arthritis in United Arab Emirates: A Focus on Interleukin-17 Inhibitors

open access: yesOpen Access Rheumatology: Research and Reviews
Ahmed Abogamal,1 Humeira Badsha,2 Suad Hannawi,3 Ghita Harifi,4 Bhavna Khan,2 Atheer Al Ansari,5 Khalid A Alnaqbi,6,7 Ahmed S Zayat,8 Shady Ibrahim,9 Mohamed Taher,9 Rajaie Namas10 1Rheumatology Department, Al-Azhar University and Zahra Hospital Dubai ...
Abogamal A   +10 more
doaj  

Family physicians' information seeking behaviors: A survey comparison with other specialties

open access: yesBMC Medical Informatics and Decision Making, 2005
Background Using technology to access clinical information has become a critical skill for family physicians. The aims of this study were to assess the way family physicians use the Internet to look for clinical information and how their patterns vary ...
Kristofco Robert   +3 more
doaj   +1 more source

A Snapshot of U.S. Physicians: Key Findings From the 2008 Health Tracking Physician Survey [PDF]

open access: yes, 2009
Analyzes survey data on U.S. physicians' compensation system, career satisfaction, acceptance of new patients, managed care contracts, and charity care provision by demographics, type of practice, specialty, geographic location, and other ...
Alwyn Cassil   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Defensive Effect of Medical Practice Policies in Malpractice Litigation [PDF]

open access: yes, 1991
The theoretical prospects for medical practice policies to reform malpractice law by giving conclusive defensive effect to medical custom were studied.
Hall, Mark A.
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Clinical analysis of the elderly patients with chronic subdural hematoma treated by trepanation and drainage under multi-disciplinary team

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To explore the multi-disciplinary diagnosis and treatment mode of elderly patients with chronic subdural hematoma (CSDH), and the effect and safety of trepanation and drainage under this mode. Methods A total of 37 elderly patients with CSDH (≥
Xue-you XU   +8 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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