Results 81 to 90 of about 451,692 (296)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Innovations and Experiments in Uses of Health Manpower—The Effect of Licensure Laws [PDF]

, 1967
Time-resolved optical spin orientation is employed to study spin dynamics of I * and I-1* excitons bound to isoelectronic centers in bulk ZnO. It is found that spin orientation at the exciton ground state can be generated using resonant excitation via a ...
Buyanova, Irina, Chen, Shula, Chen, Weimin   +2 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Gender differences in prescribing patterns for patients with Parkinson’s disease in Japan: a retrospective observational study using insurance claims databases

Frontiers in Neurology
BackgroundParkinson’s disease (PD) is a neurodegenerative disorder, with increasing prevalence among aging populations. Gender differences in PD extend to symptom presentation and treatment response, suggesting the need for gender-specific management ...
Morinobu Seki, Morinobu Seki, Yayoi Kawata, Ayako Hayashi, Shinji Fujimoto   +4 more
doaj   +1 more source

Physician Organization in Relation to Quality and Efficiency of Care: A Synthesis of Recent Literature [PDF]

, 2008
Summarizes research linking cohesion, scale, and affiliation in physician groups to improved quality and efficiency. Discusses implications for promoting delivery system reform through physician group organization and changes to the payment ...
Laura Tollen
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Clinical variability in complementary feeding counseling in Türkiye: results from a pediatrician survey

Frontiers in Pediatrics
IntroductionComplementary feeding (CF) is a critical period in infant nutrition, during which pediatricians play a pivotal role. This study aimed to examine CF recommendations by pediatricians in Türkiye, focusing on differences based on infants’ allergy
Nalan Karabayır, Nalan Karabayır, Demet Deniz Bilgin, Demet Deniz Bilgin, Mine Başıbüyük, Mine Başıbüyük, Övgü Büke, Övgü Büke   +7 more
doaj   +1 more source

Factors for and against establishing and working in private practice correlated with work-related behavior and experience patterns of Ferman physicians in Schleswig-Holstein: A 2-year longitudinal study

International Journal of Occupational Medicine and Environmental Health, 2017
Objectives: To identify factors in favor of or against establishing and working in private practice, to determine the quality of life and work-related behavior and experience patterns of German physicians working in private practice, and to analyze the ...
Edgar Voltmer, Claudia Spahn, Erica Frank   +2 more
doaj   +1 more source

Association of Clinical Characteristics With Variation in Emergency Physician Preferences for Patients. [PDF]

, 2020
Importance:Much of the wide variation in health care has been associated with practice variation among physicians. Physicians choosing to see patients with more (or fewer) care needs could also produce variations in care observed across physicians ...
Chang, Cindy Y, Obermeyer, Ziad
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source