Results 81 to 90 of about 6,191,678 (292)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A panel data study of physicians’ labor supply: The case of Norway [PDF]

Physicians are key personnel in a sector which is important due to its size as well as the quality of service it provides. We estimate the labor supply of physicians employed at hospitals in Norway, using personnel register data merged with other public ...
Holmås, Tor Helge, Bratberg, Espen, Baltagi, Badi H.   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Rural Idaho Family Physicians’ Scope of Practice [PDF]

, 2010
Context: Scope of practice is an important factor in both training and recruiting rural family physicians. Purpose: To assess rural Idaho family physicians’ scope of practice and to examine variations in scope of practice across variables such as gender,
Miller, Carissa Moffat, Nukui, Ayaka, Baker, Ed, Epperly, Ted, Schmitz, David   +4 more
core  

Gender differences in prescribing patterns for patients with Parkinson’s disease in Japan: a retrospective observational study using insurance claims databases

Frontiers in Neurology
BackgroundParkinson’s disease (PD) is a neurodegenerative disorder, with increasing prevalence among aging populations. Gender differences in PD extend to symptom presentation and treatment response, suggesting the need for gender-specific management ...
Morinobu Seki, Morinobu Seki, Yayoi Kawata, Ayako Hayashi, Shinji Fujimoto   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Personal Use of Drug Samples by Physicians and Office Staff

, 1997
CONTEXT: Pharmaceutical samples are commonly used in ambulatory care settings. There is limited research on their use or impact on health care providers and patients. OBJECTIVE: To determine the extent of personal use of drug samples over a 1-year period
McCabe, Jennifer, Westfall, John M., Nicholas, Richard A.   +2 more
core   +1 more source

Clinical variability in complementary feeding counseling in Türkiye: results from a pediatrician survey

Frontiers in Pediatrics
IntroductionComplementary feeding (CF) is a critical period in infant nutrition, during which pediatricians play a pivotal role. This study aimed to examine CF recommendations by pediatricians in Türkiye, focusing on differences based on infants’ allergy
Nalan Karabayır, Nalan Karabayır, Demet Deniz Bilgin, Demet Deniz Bilgin, Mine Başıbüyük, Mine Başıbüyük, Övgü Büke, Övgü Büke   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The evolution of nursing in Australian general practice: a comparative analysis of workforce surveys ten years on [PDF]

, 2014
This article describes the current demographic and employment characteristics of Australian nurses working in general practice, and explores trends in their role over time. Abstract: Background Nursing in Australian general practice has grown rapidly
Samantha A.M. Young, Rajneesh Kaur, Salamonson, Y, Kaur, R ; https://orcid.org/, Samantha AM Young, Halcomb, EJ, Patricia M Davidson, Davidson, Patricia M., Elizabeth J Halcomb, Patricia M. Davidson, Kaur, R, Halcomb, Elizabeth, Davidson, PM ; https://orcid.org/, Elizabeth J. Halcomb, Young, SAM, Yenna Salamonson, Young, Samantha A., Davidson, PM, Salamonson, Yenna (R8521), Kaur, Rajneesh   +19 more
core   +2 more sources