Results 131 to 140 of about 14,651,094 (400)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Effective Pre-school and Primary Education 3-11 Project (EPPE 3-11): Variations in Teacher and Pupil Behaviours in Year 5 Classes [PDF]

, 2006
The EPPE 3-11 Project builds on the work of the earlier Effective Provision of Pre-School Education (EPPE) project, which was the first major longitudinal study in Europe to investigate the impact of pre-school provision on a national sample of young ...
Barreau, Sofka, Manni, Laura, Melhuish, Edward, Sammons, Pamela, Siraj-Blatchford, Iram, Sylva, Kathy, Taggart, Brenda   +6 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Information technology as boundary object for transformational learning [PDF]

, 2009
Collaborative work is considered as a way to improve productivity and value generation in construction. However, recent research demonstrates that socio-cognitive factors related to fragmentation of specialized knowledge may hinder team performance. New
Forgues, Daniel, Koskela, Lauri, Lejeune, Albert   +2 more
core   +1 more source

Blepharitis Preferred Practice Pattern® [PDF]

Ophthalmology, 2019
Guillermo, Amescua, Esen K, Akpek, Marjan, Farid, Francisco J, Garcia-Ferrer, Amy, Lin, Michelle K, Rhee, Divya M, Varu, David C, Musch, Steven P, Dunn, Francis S, Mah   +9 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Adult Strabismus Preferred Practice Pattern® [PDF]

Ophthalmology, 2020
Linda R, Dagi, Federico G, Velez, Steven M, Archer, Hatice Tuba, Atalay, Brian N, Campolattaro, Jonathan M, Holmes, Natalie C, Kerr, Burton J, Kushner, Sarah E, Mackinnon, Evelyn A, Paysse, Matthew Simon, Pihlblad, Stacy L, Pineles, Mitchell B, Strominger, David R, Stager, David, Stager, Hilda, Capo   +15 more
openaire   +3 more sources

Variations in Practice Patterns among Neurosurgeons and Orthopaedic Surgeons in the Management of Spinal Disorders [PDF]

, 2011
Manzar Hussain, Sadaf Nasir, Amber Moed, Ghulam Murtaza   +3 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source