Results 151 to 160 of about 14,060,785 (382)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Physician Dual Practice: Access Enhancement or Demand Inducement? [PDF]

In many developing countries, the majority of physicians employed in government clinics also have a private practice. We develop a simple model to show that allowing dual practice helps low-income governments retain skilled physicians to assure patient ...
Anupa Bir, Karen Eggleston
core  

Validation of hardware events for successful performance pattern identification in High Performance Computing

, 2017
Hardware performance monitoring (HPM) is a crucial ingredient of performance analysis tools. While there are interfaces like LIKWID, PAPI or the kernel interface perf\_event which provide HPM access with some additional features, many higher level tools ...
Eitzinger, Jan, Hager, Georg, Röhl, Thomas, Wellein, Gerhard   +3 more
core   +1 more source

Detecting Dark Patterns in User Interfaces Using Logistic Regression and Bag-of-Words Representation [PDF]

arXiv
Dark patterns in user interfaces represent deceptive design practices intended to manipulate users' behavior, often leading to unintended consequences such as coerced purchases, involuntary data disclosures, or user frustration. Detecting and mitigating these dark patterns is crucial for promoting transparency, trust, and ethical design practices in ...
arxiv  

Combinatorial Optimization in Pattern Assembly [PDF]

arXiv, 2013
Pattern self-assembly tile set synthesis (PATS) is a combinatorial optimization problem which aim at minimizing a rectilinear tile assembly system (RTAS) that uniquely self-assembles a given rectangular pattern, and is known to be NP-hard. PATS gets practically meaningful when it is parameterized by a constant c such that any given pattern is ...
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Changes in Retina Practice Patterns During the COVID-19 Pandemic in the Philippines

Clinical Ophthalmology, 2021
Albert John Bromeo,1 Patricia Grulla-Quilendrino,1 Sweet Jorlene Lerit,1 Myron Carlo Gomez,1 Cheryl A Arcinue,1,2 Ralph Anthony De Jesus,1 Amadeo Veloso Jnr1 1Asian Eye Institute, Makati, Philippines; 2Department of Ophthalmology and Visual Sciences ...
Bromeo AJ, Grulla-Quilendrino P, Lerit SJ, Gomez MC, Arcinue CA, De Jesus RA, Veloso Jnr A   +6 more
doaj  

Pattern Encoding on the Poincare Sphere [PDF]

arXiv, 2014
This paper presents a convenient graphical tool for encoding visual patterns (such as image patches and image atoms) as point constellations in a space spanned by perceptual features and with a clear geometrical interpretation. General theory and a practical pattern encoding scheme are presented, inspired by encoding polarization states of a light wave
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source