Results 61 to 70 of about 882,336 (269)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Regional and Temporal Variations in Comorbidity Among US Dialysis Patients: A Longitudinal Study of Medicare Claims Data

open access: yesInquiry: The Journal of Health Care Organization, Provision, and Financing, 2018
Medicare claims data are commonly used to query comorbidities for case-mix adjustment in research of patients with end-stage renal disease (ESRD) in the United States.
Yi Mu PhD   +4 more
doaj   +1 more source

Management of cataracts and ectopia lentis in children: Practice patterns of pediatric ophthalmologists in India

open access: yesIndian Journal of Ophthalmology, 2017
Purpose: To analyze the current practice patterns of Indian pediatric ophthalmologists in the management of lens anomalies. This study was conducted in a tertiary eye care hospital and involved an online questionnaire survey for practicing pediatric ...
Vasudha Kemmanu   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

"Tenure Track" System for University Teachers: Practice Patterns and Institution Optimization

open access: yesJiaoshi jiaoyu xuebao
Since the late 1990s, with a few universities implementing the teacher appointment reform, the practice around the "tenure track" system for university teachers has continued to deepen, forming different institution change models in the process of ...
LI Zhifeng, RAN Wenxiang, ZHAO Yingchuan
doaj   +1 more source

A Cross-Sectional Study on Prescription Patterns of Short-Acting β2-Agonists in Patients with Asthma: Results from the SABINA III Colombia Cohort

open access: yesJournal of Asthma and Allergy, 2022
John Carlos Pedrozo-Pupo,1 Manuel Conrado Pacheco Gallego,2 Iván de Jesús Baños Álvarez,3 Rodolfo Antonio Jaller Raad,4 Andrea Carolina Caballero Pinilla,5 Humberto Reynales Londoño,6 Laura Bernal Villada,7 Maarten Beekman8 1PREVICARE LTDA.
Pedrozo-Pupo JC   +7 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Practice and Malpractice: Physician Responses to the Liability 'Crisis'

open access: yesJournal of Public and Professional Sociology, 2008
Mississippi is a largely rural state with many poor and unhealthy residents who are chronically underserved by the smallest per capita physician workforce in the nation.
Lynne Cossman , Debra Street
doaj   +1 more source

Implementing Bilingual Pattern Practice [PDF]

open access: yesRELC Journal, 2015
This article describes how semi-communicative bilingual drills were implemented in a four-month course in pedagogical English for a group of ten Polish adult learners. When the course was over, the learners were asked to evaluate the procedure by filling in a questionnaire.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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