Results 101 to 110 of about 8,841,562 (288)
ANALYTICAL REVIEW OF THE NORMATIVE BASE TO PROVIDE THE GOOD QUALITY OF PRECLINICAL STUDIES IN RUSSIA
Разработка и регистрация лекарственных средств, 2019 The main goal of preclinical studiesis the development of effective, high-quality and safe drugs. The task of preclinical studiesis to obtain exhaustive information, reliable and reproducible results.
A. I. Selezneva +5 more
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Private metropolitan telepsychiatry in Australia during Covid-19: current practice and future developments [PDF]
, 2020 Jeffrey CL Looi, William Pring
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 The article presents data on the development of a technique for determination of intrinsic viscosity of injectable drug with chondroitin sodium sulfate. A 0.2 M solution of sodium chloride was use as a solvent to eliminate polyelectrolyte swelling.
K. R. Saveleva +3 more
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Quaestiones GeographicaeMobility is an important source of greenhouse gas (GHG) emissions and a major contributor to human-induced climate change. Much of these emissions result from urban residents’ travel within urban areas (i.e.
Czepkiewicz Michał +3 more
doaj +1 more source
Bridging New Technology Into Clinical Practice With Mobile Apps, Electronic Patient-Reported Outcomes, and Wearables [PDF]
, 2022 Hannah Dzimitrowicz +3 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Science communication: a messy conundrum of practice, research and theory [PDF]
, 2022 Jenni Metcalfe
openalex +1 more source