Results 171 to 180 of about 13,844,596 (408)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

ANALYTICAL REVIEW OF THE NORMATIVE BASE TO PROVIDE THE GOOD QUALITY OF PRECLINICAL STUDIES IN RUSSIA

open access: yesРазработка и регистрация лекарственных средств, 2019
The main goal of preclinical studiesis the development of effective, high-quality and safe drugs. The task of preclinical studiesis to obtain exhaustive information, reliable and reproducible results.
A. I. Selezneva   +5 more
doaj  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Social and Geographical Distribution of Mobility-Related Greenhouse Gas Emissions in Poznań and Tri-City Functional Urban Areas

open access: yesQuaestiones Geographicae
Mobility is an important source of greenhouse gas (GHG) emissions and a major contributor to human-induced climate change. Much of these emissions result from urban residents’ travel within urban areas (i.e.
Czepkiewicz Michał   +3 more
doaj   +1 more source

Generating Piano Practice Policy with a Gaussian Process [PDF]

open access: yesarXiv
A typical process of learning to play a piece on a piano consists of a progression through a series of practice units that focus on individual dimensions of the skill, the so-called practice modes. Practice modes in learning to play music comprise a particularly large set of possibilities, such as hand coordination, posture, articulation, ability to ...
arxiv  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Pharmaceutical Advertising and Public Perceptions in Saudi Arabia

open access: yesPharmacy
Introduction: As the pharmaceutical advertising landscape evolves with digital advancements, this study examines public awareness and perceptions of medication advertisements in Saudi Arabia.
Mohammed A. Alnuhait   +11 more
doaj   +1 more source

Safe practice in using wire rope in mines [PDF]

open access: green, 1920
R.H. Kudlich, O. P. Hood
openalex   +1 more source

Wittgenstein on rules and practices [PDF]

open access: yes, 2002
Some readers of Wittgenstein---I discuss Robert Brandom---think that his writings contain a regress argument showing that the notion of participating in a practice is more basic than the notion of following a rule, in explanations of linguistic ...
Mccullagh, Mark
core  

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