Results 1 to 10 of about 28 (28)

Avoiding Routine Oxygen Therapy in Patients With Myocardial Infarction Saves Significant Expenditure for the Health Care System—Insights From the Randomized DETO2X-AMI Trial

Frontiers in Public Health, 2022
Background: Myocardial infarction (MI) occurs frequently and requires considerable health care resources. It is important to ensure that the treatments which are provided are both clinically effective and economically justifiable.
Robin Hofmann, Tamrat Befekadu Abebe, Johan Herlitz, Stefan K. James, Stefan K. James, David Erlinge, Joakim Alfredsson, Joakim Alfredsson, Tomas Jernberg, Thomas Kellerth, Annica Ravn-Fischer, Annica Ravn-Fischer, Bertil Lindahl, Bertil Lindahl, Sophie Langenskiöld, DETO2X-SWEDEHEART Investigators   +15 more
doaj   +1 more source

The Effects of a Mindfulness Program on Mental Health in Students at an Undergraduate Program for Teacher Education: A Randomized Controlled Trial in Real-Life

Frontiers in Psychology, 2021
Background: In this study, we aimed to investigate the effects of a mindfulness program including Mindfulness-Based Stress Reduction (MBSR) on the mental health of student teachers when offered at their educational institution in a real-life context ...
Lise Juul, Eva Brorsen, Katinka Gøtzsche, Birgitte Lund Nielsen, Lone Overby Fjorback   +4 more
doaj   +1 more source

Meta-research on pragmatism of randomized trials: rationale and design of the PragMeta database

Trials, 2023
Background Pragmatic trials provide decision-oriented, real-world evidence that is highly applicable and generalizable. The interest in real-world evidence is fueled by the assumption that effects in the “real-world” are different to effects obtained ...
Julian Hirt, Perrine Janiaud, Pascal Düblin, Lars G. Hemkens   +3 more
doaj   +1 more source

Stress-free Everyday LiFe for Children and Adolescents REsearch (SELFCARE): a protocol for a cluster randomised trial testing a school teacher training programme to teach mindfulness (“.b”)

BMC Psychology, 2021
Background There is a call for sustainable, evidence-based interventions in schools to promote mental health in schoolchildren. Our primary aim of this trial is to evaluate the effectiveness in vulnerable pupils of a school teacher training programme to ...
Lise Juul, Morten Frydenberg, Michelle Sand Beck, Lone Overby Fjorback   +3 more
doaj   +1 more source

Best-BRA (Is subpectoral or prepectoral implant placement best in immediate breast reconstruction?): a protocol for a pilot randomised controlled trial of subpectoral versus prepectoral immediate implant-based breast reconstruction in women following mastectomy

BMJ Open, 2021
Background Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure following mastectomy. IBBR techniques are evolving rapidly, with mesh-assisted subpectoral reconstruction becoming the standard of care and more
Kirsty Roberts, Clare Clement, Jodi Taylor, Chris Metcalfe, William Hollingworth, Shelley Potter, Athene Lane, Joanna Skillman, Steven Thrush, Lisa Whisker, Nicola Mills, Katherine Fairhurst, Patricia Fairbrother, Chris Holcombe, Ramsey Cutress   +14 more
doaj   +1 more source

A pilot randomised trial comparing a mindfulness-based stress reduction course, a locally-developed stress reduction intervention and a waiting list control group in a real-life municipal health care setting

BMC Public Health, 2020
Background The purpose of the present study was to conduct a pilot randomised controlled trial (RCT) to lend support to a larger effectiveness RCT comparing Mindfulness-Based Stress Reduction (MBSR), a locally-developed stress reduction intervention (LSR)
Lise Juul, Karen Johanne Pallesen, Mette Bjerggaard, Corina Nielsen, Lone Overby Fjorback   +4 more
doaj   +1 more source

Prepectoral no mesh versus mesh immediate implant-based reconstruction after mastectomy (Restore-B): a multicentre single-blinded randomised controlled feasibility study protocol

BMJ Open
Introduction Breast cancer is common and women requiring mastectomy will be offered a breast reconstruction if they are surgically suitable candidate. Breast reconstruction can be performed at the same time as the mastectomy (immediate) or delayed to a ...
, Sue Ziebland, Amy Taylor, Pankaj Roy, Rachel Rolph, Joanna Wakefield-Scurr, Michael Douek, Marcelle Bernstein, Sarah Markham, Avi Agrawal, Jonathan Alistair Cook, Dibendu Betal, Richard Rainsbury, Cynthia Iglesias, Suzy Cleator, Brendan Smith, Charles Malyon, Jessica Scaife, Aimee Hennessy, Jennifer Rusby, Riccardo Bonomi, Edward St-John, Timothy Martyn Hill, Mark HoAsjoe, Jack Elkes   +24 more
doaj   +1 more source

Registry-based randomised controlled trials: conduct, advantages and challenges—a systematic review

Trials
Background Registry-based randomised controlled trials (rRCTs) have been described as pragmatic studies utilising patient data embedded in large-scale registries to facilitate key clinical trial procedures including recruitment, randomisation and the ...
Frances Shiely, Niamh O Shea, Ellen Murphy, Joseph Eustace   +3 more
doaj   +1 more source

Implementation Challenges for a Multisite Advance Care Planning Pragmatic Trial: Lessons Learned

Journal of Pain and Symptom Management, 2023
Neil S Wenger, Rebecca Sudore, Anne Walling   +2 more
exaly  

Improved transition to adult care in youth with type 1 diabetes: a pragmatic clinical trial

Diabetologia, 2021
Daniele Pacaud, Sonia Butalia, Julia Mercer   +2 more
exaly