Results 121 to 130 of about 6,694,831 (167)

Definition and recommendations for trial methods for evaluating dentin hypersensitivity: A hybrid AI‐assisted scoping review and Delphi consensus process

Periodontology 2000, EarlyView.
Abstract Background Dentin hypersensitivity (DH) is a common yet inconsistently defined condition impacting oral health and quality of life. Variability in diagnostic criteria and trial methodologies has limited comparability of previous research. Objectives To map current definitions, diagnostic frameworks, and clinical trial methodologies in DH ...
Alexander J. Pollard, Tom J. Pollard, Anne‐Marie Glenny, Jan Clarkson, Tanya Walsh, Maria Davies, Thomas Sounack, Matthew Wright, Joon Seong, Joshua Twigg, Rupert Austin, Rossana Izzetti, Crystal Marruganti, Robert Newcombe, Rebecca Bullock, Nicola X. West   +15 more
wiley   +1 more source

Operationalizing Precision Medicine in Drug Development: Predictive Biomarkers, Companion Diagnostics, and Regulatory Pathways

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 914-929, October 2026.
Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg, José M.A. Moreira   +1 more
wiley   +1 more source

Robotic Computer‐Assisted Dental Implant Surgery Versus Free‐Hand and Guided Techniques: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Clinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.
ABSTRACT Background Robotic computer‐assisted implant surgery (r‐CAIS) aims to improve implant placement trueness, but existing reviews include heterogeneous designs, and no review has exclusively synthesized RCTs to date. This review aimed to evaluate the positional trueness and clinical outcomes of r‐CAIS compared with free‐hand implant surgery (FHIS)
Sultan Ainoosah, Redhwan Saleh Al‐Gabri, Omar M. Alaryani, Ahmad Abdulkareem Alnazzawi, Ahmed E. Farghal, Ahmed Yaseen Alqutaibi   +5 more
wiley   +1 more source

Non‐invasive biomarkers in biliary atresia: A scoping review of fibrosis assessment, translational readiness and clinical implementation gaps

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Biomarkers are positioned by their highest developmental stage. Most biomarkers remain in exploratory phases, with serum MMP‐7 and elastography showing the greatest translational maturity. This highlights the primary challenge is the transition from biomarker discovery to clinical implementation.
Elizabeth Brits, Stephen Brown, Lezelle Botes, Michael Pienaar   +3 more
wiley   +1 more source

Cytological Features of Clear Cell Sarcoma in Exfoliative and Effusion Cytology Specimen—A Case Report and Literature Review

Diagnostic Cytopathology, Volume 54, Issue 10, Page 731-737, October 2026.
ABSTRACT Clear cell sarcoma of soft tissue (CCSST) with malignant effusion is a rare yet clinically aggressive appearance, which may pose a diagnostic pitfall with its overlapping cytomorphologic features with metastatic melanoma and carcinoma.
William H. Wu, Joanna K. M. Ng, Joshua J. X. Li   +2 more
wiley   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Characteristics and Specific Aspects of the Therapeutic Alliance in Physiotherapy Care: A Qualitative Study in France

Physiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Background and Purpose Therapeutic alliance (TA) refers to mutuality and congruence concerning the bonds, goals, and tasks shared between the physiotherapist and patient. It relies on positive connections through partnership, communication, empathy, and mutual respect.
Alice Jugand, Maxi Miciak, Parker Lay, Michael H. Bernstein, Leo Druart   +4 more
wiley   +1 more source

Methodological Approaches for Ultrasound Assessment of Peripheral and Abdominal Muscle Thickness in Intensive Care: A Scoping Review and Proposed Reporting Framework

Physiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Objective To map and synthesize methodological approaches used for ultrasound (US) assessment of peripheral (upper‐ and lower‐limb) and abdominal muscle thickness in critically ill patients, and to propose a preliminary Standard Operating Procedure (SOP) as a structured reporting framework.
Pedro Vinicius Porfirio, Wagner Souza Leite, Layane Santana Pereira Costa, Pedro Henrique de Moura, Ana Célia Oliveira dos Santos, Emanuel Fernandes Ferreira da Silva Junior, Elaine Araújo de Souza, Marismar Fernandes do Nascimento, Helga Cecilia Muniz de Souza, Shirley Lima Campos   +9 more
wiley   +1 more source

Effects of a Cycling‐Based Aerobic Exercise Program Versus a Resistance and Neuromuscular Exercise Program on Exercise‐Induced Hypoalgesia in Knee Osteoarthritis: A Study Protocol for a Randomized Clinical Trial

Physiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Background and Purpose Exercise therapy is a core treatment for knee osteoarthritis (KOA), but the effects of different exercise modalities on endogenous pain modulation remain unclear. This trial will compare a cycling‐based aerobic exercise program with a resistance and neuromuscular exercise program on exercise‐induced hypoalgesia (EIH) in ...
Bruno Ruocco Verengue, Lisa C. Carlesso, Barbara Greco Miura, Aron Charles Barbosa da Silva, Patrícia Gabrielle dos Santos, Almir Vieira Dibai‐Filho, Cid André Fidelis‐de‐Paula‐Gomes   +6 more
wiley   +1 more source

Measuring Coping Strategies in Daily Life: A Systematic Review of Experience Sampling Methodology and Daily Diary Studies

Stress and Health, Volume 42, Issue 5, October 2026.
ABSTRACT Advances in daily diary methods and experience sampling method (ESM) have improved the study of coping strategies in daily life and their role in shaping health and well‐being. In this review, we examine study designs, measurement approaches, and analytical practices used to investigate coping in natural contexts.
Petra Mikolič Brence, Sara Bugarinović, Gaja Zager Kocjan   +2 more
wiley   +1 more source