ABSTRACT Purpose 1H MRS lactate measurements are potentially valuable for studying energy metabolism in working skeletal muscle, but some technical obstacles need to be overcome. Spectral filtering to isolate the lactate signal from overlapping lipid resonances shows promise.
Kostiantyn Repnin +6 more
wiley +1 more source
Running a clinical trial remotely: Lessons learnt from a decentralised multicentre randomised controlled trial evaluating a digital health intervention for Chronic Kidney Disease. [PDF]
Sohansoha GK +6 more
europepmc +1 more source
ABSTRACT Purpose We present a method for absolute quantification of deuterated metabolites in vivo at 7T. We describe acquisition protocols and an analysis pipeline compatible with 7T Terra MRIs. We apply them using a 2H/1H receive array in healthy volunteers and glioblastoma patients.
Jabrane Karkouri +12 more
wiley +1 more source
Effect of nonsteroidal anti-inflammatory drugs on union, opioid utilization, and pain management for tibial fractures (NSAID Trial): a pragmatic randomized clinical trial protocol. [PDF]
Higgins TF +6 more
europepmc +1 more source
Abstract Background Body composition and energy metabolism assessments are central to nutrition care but remain underused. This study evaluated dietitians’ access, use, education, and beliefs toward these assessments, and the impact of an educational session.
Camila E. Orsso +17 more
wiley +1 more source
C-prior-implementation of the MAINTAIN instrument for patients with spinal pain: study protocol for a randomized clinical trial. [PDF]
Funabashi M +7 more
europepmc +1 more source
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella +9 more
wiley +1 more source
Pragmatic paradigm for patient-reported outcome measure selection in lymphoma clinical trials: a rapid review study. [PDF]
Guo JD +4 more
europepmc +1 more source
Surgical versus non‑surgical treatment of proximal humerus fracture in patients aged 50-65 years: young shoulder CARE (displaCed proximAl humeRus fracturE) trial-a pragmatic randomized controlled trial study protocol. [PDF]
Houkjær L +6 more
europepmc +1 more source

