Creativity and its link to epilepsy
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Platform for the Evaluation of innovations in Radiation oncology through registry-based conduct of multi-centric pragmatic randomized trials: PERa implementation. [PDF]
Giguère P +13 more
europepmc +1 more source
ABSTRACT Objectives Dravet syndrome (DS) is a severe, drug‐resistant developmental and epileptic encephalopathy (DEE) that requires polytherapy for adequate seizure control. The need to combine multiple antiseizure medications (ASMs), together with variability in seizure types, safety considerations, and evolving patient needs, makes treatment ...
Elaine Wirrell, Joseph Sullivan
wiley +1 more source
Response to the FDA Dosage Optimization Draft Guidance for Radiopharmaceutical Therapies. [PDF]
Kiess AP +3 more
europepmc +1 more source
Abstract Objective About one third of epilepsy patients are drug‐resistant. Resective epilepsy surgery remains a key treatment option but depends critically on accurate identification of the seizure onset zone (SOZ), which is still guided mainly by subjective visual inspection of electrophysiological signals.
Tena Dubcek +5 more
wiley +1 more source
Clinical high-risk vs. population-level prevention of mental disorders: a false dichotomy. [PDF]
Fusar-Poli P, Oliver D.
europepmc +1 more source
Cumulative electroconvulsive therapy sessions and focal epilepsy: A nationwide cohort study in Japan
Abstract Objective Electroconvulsive therapy (ECT) is widely used for severe psychiatric disorders, yet concerns remain regarding possible epileptogenic effects associated with prolonged or repeated exposure. We examined the association between cumulative ECT sessions and focal epilepsy in a nationwide Japanese cohort.
Masahiro Hata +4 more
wiley +1 more source
Bayesian adaptive cluster-randomized designs with long primary endpoints for pragmatic weight loss studies implemented in rural communities. [PDF]
Bernal J, Wick J, Befort C, Gajewski B.
europepmc +1 more source
Editorial: Digital mindfulness in primary care: enhancing health through technology. [PDF]
Chen H, Tu Y, Zeng S, Liu C.
europepmc +1 more source
Optimising clinical trial design choices in inflammatory bowel disease. [PDF]
Bossuyt P +4 more
europepmc +1 more source

