Results 271 to 280 of about 444,144 (378)

Expedited Approval in Oncology: A Study of European Regulators' Perspectives and Trade‐Offs

Clinical Pharmacology &Therapeutics, EarlyView.
The purpose of this study was to describe the perspectives and trade‐offs of EU regulators about expedited approvals for treatments of patients with advanced cancer. The study consisted of a cross‐sectional survey with assessors and experts from the network of the European Medicines Agency (EMA).
Francesco Pignatti, Filip Josephson, Pierre Demolis, Olli Tenhunen, Elias Péan, Douwe Postmus   +5 more
wiley   +1 more source

A Classroom-Based Intervention for Reducing Sedentary Behavior and Improving Spinal Health: Pragmatic Stepped-Wedge Feasibility Randomized Controlled Trial. [PDF]

JMIR Form Res
Fisher D, Maart R, Thabane L, Louw Q.
europepmc   +1 more source

Pragmatic Aspects of Type-Directed Partial Evaluation

, 1996
Olivier Danvy
openalex   +2 more sources

Alemtuzumab Exposure and T Lymphocyte Depletion: A Population Pharmacokinetic‐Pharmacodynamic Model of Alemtuzumab Induction Therapy for Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Alemtuzumab is a T cell‐depleting monoclonal antibody that is used for the prevention of kidney transplant rejection. The duration of lymphodepletion after the current standard induction therapy dose is likely longer than necessary, resulting in prolonged T cell lymphopenia with the associated risk of infections. Here, the interplay between alemtuzumab
Lukas K. van Vugt, Tom C. Zwart, Suzanne Bezstarosti, Sebastiaan Heidt, Marlies E. J. Reinders, Dennis A. Hesselink, Aiko P. J. de Vries, Brenda C. M. de Winter, Dirk Jan A. R. Moes   +8 more
wiley   +1 more source

Approaches towards pragmatic language assessment in Indian pre-schoolers: A survey among speech-language pathologists. [PDF]

F1000Res
Rasheeka S, Karuppali S, Bhat J, Mohan M, Varghese A.   +4 more
europepmc   +1 more source

Navigating the Real World: A Scoping Review of Structured Frameworks to Effectively Identify, Evaluate, and Select Real‐World Data Sources for Fit‐for‐Purpose Studies

Clinical Pharmacology &Therapeutics, EarlyView.
The potential of real‐world data (RWD), particularly from patient registries, has been increasingly recognized over the last decade by academia, regulators, and health technology assessment (HTA) bodies for its role in assessing a product's effectiveness and supporting regulatory submissions.
Sonia Zebachi, Julien Tanniou, Elisabeth Bakker, Sieta T. de Vries, Rossella Di Bidino, Entela Xoxi, Anna Glaser, Gianluigi Savarese, Jan Hillert, Peter G. M. Mol, Kelly Plueschke, Billy Amzal, Ghinwa Y. Hayek, Jeverson Moreira   +13 more
wiley   +1 more source

Pragmatic language production in mood and psychotic disorders a systematic review and meta-analysis

Meister F, Sellier-Silva M, Melshin G, Mouslih EC, Zaher F, Sattari R, Wei H, Mekideche N, Bambini V, Voppel A, Palaniyappan L.   +10 more
europepmc   +1 more source

Impact of Hearing Loss Type on Linguistic Development in Children: A Cross-Sectional Study. [PDF]

Audiol Res
Porcar-Gozalbo N, López-Zamora M, Valles-González B, Cano-Villagrasa A.   +3 more
europepmc   +1 more source

Pharmacogenetic Implementation Studies—Lessons Learned From the PREPARE Study

Clinical Pharmacology &Therapeutics, EarlyView.
The Ubiquitous Pharmacogenomics consortium (www.upgx.eu) has recently completed and published the Preemptive Pharmacogenomic Testing for Preventing Adverse Drug Reactions (PREPARE) study on the implementation of panel‐based pharmacogenetic testing. PREPARE has provided interesting lessons for the design, execution, and interpretation of future clinical
Henk‐Jan Guchelaar, Cathelijne H. van der Wouden, Lisanne E. N. Manson, Heshu Abdullah‐Koolmees, Kathrin Blagec, Tanja Blagus, Stefan Böhringer, Erika Cecchin, Ka‐Chun Cheung, Vera H. M. Deneer, Siv Jonsson, Candace Joefield‐Roka, Katja S. Just, Mats O. Karlsson, Lidija Konta, Rudolf Koopmann, Marjolein Kriek, Thorsten Lehr, Christina Mitropoulou, Victoria Rollinson, Rossana Roncato, Matthias Samwald, Elke Schaeffeler, Maria Skokou, Matthias Schwab, Daniela Steinberger, Julia C. Stingl, Roman Tremmel, Richard M. Turner, Mandy H. van Rhenen, Cristina L. Dávila‐Fajardo, Vita Dolžan, George P. Patrinos, Munir Pirmohamed, Gere Sunder‐Plassmann, Giuseppe Toffoli, Jesse J. Swen, Ubiquitous Pharmacogenomics Consortium   +37 more
wiley   +1 more source

Looking for social pragmatic communication disorder in the complex world of Italian special needs: an exploratory study. [PDF]

Sci Rep
Gabbatore I, Marchetti Guerrini A, Bosco FM.   +2 more
europepmc   +1 more source