Results 41 to 50 of about 9,863 (267)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Neo-pragmatism: an ethical anticipatory system

open access: yesEuropean Journal of Futures Research, 2017
In 1906 and 1907 William James delivered a series of lectures in Boston and New York. Those lectures later were distilled into a paper entitled PRAGMATISM A New Name for Some Old Ways of Thinking.
John Vodonick
doaj   +1 more source

Idealism, Pragmatism, And The Birth of Pragmatist Educational Thought in America

open access: yesEncounters in Theory and History of Education, 2023
This article articulates some of the historic as well as the main philosophic contributions to the transitional period in educational thought in America, 1866-1895.
James Scott Johnston
doaj   +1 more source

A pragmatic view on pragmatic trials

open access: yesDialogues in Clinical Neuroscience, 2011
Clinical trials have been the main tool used by the health sciences community to test and evaluate interventions, Trials can fall into two broad categories: pragmatic and explanatory. Pragmatic trials are designed to evaluate the effectiveness of interventions in real-life routine practice conditions, whereas explanatory trials aim to test whether an ...
openaire   +3 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Five Answers on Pragmatism [PDF]

open access: yesJournal of Philosophical Investigations, 2018
Prof. Haack answers a series of questions on pragmatism, beginning with the origins of this tradition in the work of Peirce and James, its evolution in the work of Dewey and Mead, and its influence beyond the United States in, for example, the Italian ...
Susan Hacck
doaj   +2 more sources

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos   +2 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

WILL TO TRUTH IN THE PHILOSOPHY OF PRAGMATISM

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2017
Purpose. Since the clear statement of the will-to-truth question as an existential has not been fulfilled before, this article is devoted to the solution of such a task.
D. Y. Snitko
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

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