Results 91 to 100 of about 18,928 (205)

Aspirin, clopidogrel and prasugrel monotherapy in patients with type 2 diabetes mellitus: a double-blind randomised controlled trial of the effects on thrombotic markers and microRNA levels

Cardiovascular Diabetology, 2020
Background Despite increased atherothrombotic risk in type 2 diabetes mellitus, (T2DM) the best preventative antithrombotic strategy remains undetermined. We defined the effects of three antiplatelet agents on functional readout and biomarker kinetics in
William A. E. Parker, Christian Schulte, Temo Barwari, Fladia Phoenix, Sam M. Pearson, Manuel Mayr, Peter J. Grant, Robert F. Storey, Ramzi A. Ajjan   +8 more
doaj   +1 more source

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention [PDF]

, 2018
OBJECTIVES: This multicenter pragmatic investigation assessed outcomes following clinical implementation of CYP2C19 genotype-guided antiplatelet therapy after percutaneous coronary intervention (PCI).
Alestock, Tameka D., Alsip, Jorge, Anderson, R. David, Ardati, Amer K., Beitelshees, Amber L., Brott, Brigitta C., Brown, Lawrence, Cavallari, Larisa H., Chumnumwat, Supatat, Clare-Salzler, Michael J., Coons, James C., Cooper-DeHoff, Rhonda M., Dave, Chintan V., Denny, Joshua C., Dillon, Chrisly, Duarte, Julio D., Elsey, Amanda R., Empey, Philip E., Gong, Yan, Hamadeh, Issam, Harada, Shuko, Hillegass, William B., Hines, Lindsay, Horenstein, Richard B., Howell, Lucius A., Jeng, Linda J.B., Johnson, Julie A., Kelemen, Mark D., Kimmel, Stephen E., Kreutz, Rolf P., Lee, Craig R., Lee, Y.M., Limdi, Nita A., Magvanjav, Oyunbileg, McDonough, Caitrin W., Montasser, May, Nelson, David R., Nutescu, Edith A., Nwaba, Devon C., Pakyz, Ruth E., Palmer, Kathleen, Peterson, Josh F., Pollin, Toni I., Pratt, Victoria M., Quinn, Alison H., Robinson, Shawn W., Schub, Jamie, Shuldiner, Alan R., Skaar, Todd C., Smith, Donald M., Sriramoju, Vindhya B., Starostik, Petr, Stevenson, James M., Stouffer, George A., Stys, Tomasz P., Varunok, Nicholas, Vesely, Mark R., Voora, Deepak, Wake, Dyson T., Weck, Karen E., Weitzel, Kristin W., Wilke, Russell A., Willig, James, Winterstein, Almut G., Zhao, Richard Y.   +64 more
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Dual Artery Compression for Patent Hemostasis and Prevention of Radial Artery Occlusion: The Quebec Terry2 Registry

Catheterization and Cardiovascular Interventions, Volume 107, Issue 5, Page 1594-1600, April 1, 2026.
ABSTRACT Background Radial artery occlusion (RAO) is a common complication following transradial artery access (TRA). Patent hemostasis is recommended to reduce RAO. Prophylactic ulnar artery compression is a technique to increase the rate of patent hemostasis.
Tomas A. Cieza, Francis Bonnenfant, Jimmy MacHaalany, Paola Ulacia‐Flores, Safia Ouarrak, Andres Ruhl, Erika Pomerleau, Joany Lapierre, Olivier F. Bertrand   +8 more
wiley   +1 more source

Prasugrel inhibits TLR7-driven autoimmunity in systemic lupus erythematosus by acetylating cGAS

Nature Communications
Systemic lupus erythematosus (SLE) has a complex, multifactorial etiology, which contributes to a lack of definitive cure and limited treatment efficacy. Here, we report that cyclic GMP-AMP synthase (cGAS) is significantly activated in SLE patients.
Zeng-Lin Guo, Li-Ming Sun, Shuai Jiang, Ming Zhao, Yuhui Li, Jinjing Qian, Yakai Fu, Chunmei Wu, Ying Yuan, Wen Xue, Shao-Zhen Jiang, Sen-Chao Yuan, Xucheng Lv, Xingxing Yang, Lehua Yin, Peng-Peng Zhu, Yu Yu, Xin Xu, Kai Wang, Qiu-Ying Han, Zhuoxin Li, Zhi-Hui Su, Xi-Ping Yu, Jiaqi Wu, Hong Cai, Tian Xia, Yuan Chen, Xue-Min Zhang, Wei-Hua Li, Ai-Ling Li, Tao Zhou, Zhanguo Li, Qiong Fu, Xinhua He, Tao Li   +34 more
doaj   +1 more source

Miscellanea. Levél a szerkesztőhöz. Folyóirat-referátumok. OH-KVÍZ [PDF]

, 2015
Levél a szerkesztőhöz. A családorvos várójában | Folyóirat-referátumok. Diabetologia A diabetes mint a stroke kockázati tényezője, nők és férfiak összehasonlítása: 64 tanulmány (775 385 egyén és 12 539 stroke) összefoglalója és metaanalízise ...
Fischer, Tamás, Gáspárdy, Géza, Nagy, Márton, Ábel, Tatjána   +3 more
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Percutaneous Coronary Intervention to Spontaneous Coronary Artery Dissection With Coexistent Takotsubo Cardiomyopathy: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
A case of spontaneous coronary artery dissection (SCAD) of the first diagonal branch (D1) with co‐existent Takotsubo Cardiomyopathy (TC), successfully revascularised with percutaneous coronary intervention (PCI). ABSTRACT Spontaneous coronary artery dissection (SCAD) is an uncommon cause of non‐atherosclerotic acute coronary syndrome (ACS) resulting in
Ahmed Elsherif, Pouya Ebrahimi, Sophia Khattak, Sudhakar George, Sohail Q. Khan   +4 more
wiley   +1 more source

Absence of differential effect of ticagrelor versus prasugrel maintenance dose on endothelial function in patients with stable coronary artery disease

Hellenic Journal of Cardiology, 2018
Background: Endothelial function may be improved by ticagrelor through adenosine-mediated mechanisms. We aimed to assess the effect of ticagrelor versus prasugrel on endothelial function in patients with stable coronary artery disease (CAD).
Ioanna Xanthopoulou, Ilianna Bei, Theodora Bampouri, Nikolaos Barampoutis, Athanasios Moulias, Periklis Davlouros, Dimitrios Alexopoulos   +6 more
doaj   +1 more source

P2Y12 platelet receptors: importance in percutaneous coronary intervention [PDF]

, 2013
Apart from their role in hemostasis and thrombosis, platelets are involved in many other biological processes such as wound healing and angiogenesis. Percutaneous coronary intervention is a highly thrombogenic procedure inducing platelets and monocytes ...
Alves, Claudia Maria Rodrigues, Caixeta, Adriano, Carvalho, Antonio Carlos, Carvalho, Leonardo, Chan, Mark, Falcão, Felipe José de Andrade   +5 more
core   +4 more sources

The risk of dyspnea in patients treated with third-generation P2Y12 inhibitors compared with clopidogrel: a meta-analysis of randomized controlled trials

BMC Cardiovascular Disorders, 2020
Background Ticagrelor and prasugrel are two third-generation oral P2Y12 inhibitors which are more commonly used in clinical practice. However, dyspnea has been consecutively reported in patients using third-generation oral P2Y12 inhibitors.
Na Zhang, Weisen Xu, Ou Li, Bing Zhang
doaj   +1 more source

Prasugrel versus adjusted high-dose clopidogrel in patients with high-on- clopidogrel platelet reactivity: the PECS-HPR randomised, multicentre study [PDF]

, 2015
Aims: Repeated loading doses (LD) of clopidogrel were shown to effectively overcome high-on-clopidogrel platelet reactivity (HPR); however, comparison to potent P2Y12-inhibitors is lacking.
Aradi, Dániel
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