Results 41 to 50 of about 12,380 (194)

Effects of Clopidogrel, Prasugrel and Ticagrelor on Microvascular Function and Platelet Reactivity in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Stenting. A Randomized, Blinded, Parallel Group Trial

Frontiers in Cardiovascular Medicine, 2021
Aims: In this pre-specified analysis of the “endothelium, stent and antiplatelet therapy” study, we investigate the impact of antiplatelet therapies on microvascular function in patients undergoing stenting for an acute coronary syndrome.Methods and ...
Boris Schnorbus, Boris Schnorbus, Kerstin Jurk, Karl J. Lackner, Caroline Welk, Thomas Münzel, Tommaso Gori, Tommaso Gori   +7 more
doaj   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

AN EXTENSIVE REVIEW ON PRASUGREL

, 2018
In an attempt prasugrel increase in the overall use of this medication comparing to the anti thembolytics like heparin and wararin, with less patients complaints includes side effects a significant portion of patients receiving the medication for off ...
Nagaraju, GV, Subrahmanyam, SN, Pavan Kumar, GV   +2 more
core   +2 more sources

Primary cardiovascular preventive effect of thiazolidinedione in adults with type 2 diabetes: A nationwide cohort study in Korea

Journal of Diabetes Investigation, EarlyView.
Among Korean adults with type 2 diabetes and no prior cardiovascular disease, thiazolidinedione use was associated with a lower risk of the primary composite outcome of stroke, myocardial infarction, hospitalization for heart failure, and all‐cause mortality compared to dipeptidyl peptidase‐4 inhibitor use. ABSTRACT Background Thiazolidinediones (TZDs)
Yun Young Choi, Jimin Jeon, Minyoul Baik, Joonsang Yoo, Jinkwon Kim   +4 more
wiley   +1 more source

Prasugrel in critically ill patients

, 2017
SummaryWhile prasugrel is indicated for the treatment of myocardial infarction, its effects in the most severely affected patients requiring intensive care is unknown, so that we measured the antiplatelet effects and sparse pharmacokinetics of prasugrel ...
Gottfried Heinz, Eva-Luise Hobl, Walter Speidl, Jolanta Siller-Matula, Thomas Staudinger, Jacek Kubica, Christian Zauner, Birgit Reiter, Christian Schoergenhofer, Bernd Jilma   +9 more
core   +1 more source

Prasugrel (Efient®) with percutaneous coronary intervention for treating acute coronary syndromes (review of TA182): systematic review and economic analysis

Health Technology Assessment, 2015
Background: Acute coronary syndromes (ACSs) are life-threatening conditions associated with acute myocardial ischaemia. There are three main types of ACS: ST segment elevation myocardial infarction (STEMI), non-ST segment elevation myocardial infarction (
Janette Greenhalgh, Adrian Bagust, Angela Boland, Kerry Dwan, Sophie Beale, Nigel Fleeman, Joanne McEntee, Yenal Dundar, Marty Richardson, Michael Fisher   +9 more
doaj   +1 more source

Safety profile of prasugrel and clopidogrel in patients with acute coronary syndromes in Switzerland.

, 2015
OBJECTIVE To assess safety up to 1 year of follow-up associated with prasugrel and clopidogrel use in a prospective cohort of patients with acute coronary syndromes (ACS).
Roffi, Marco, Carballo, D., Mach, F., Mach, François, Stähli, Barbara E, Jüni, Peter, Templin, C., Maier, W., Auer, R., Klingenberg, Roland, Carballo, David, Auer, Reto, Jaguszewski, M., Klingenberg, R., Gencer, Baris, Heg, D., Roffi, M., Matter, C.M., Templin, Christian, Nanchen, David, Lüscher, T.F., Maier, Willibald, Gencer, B., Landmesser, Ulf, Räber, L., Windecker, S., Meier, Bernhard, Heg, Dik, Jaguszewski, Milosz, Lüscher, Thomas F, Jakob, P., Windecker, Stephan, Rodondi, Nicolas, Jakob, Philipp, Nanchen, D., Vogt, Pierre, Landmesser, U., Stefanini, Giulio G, Vogt, P., Matter, Christian M, Meier, B., Jüni, P., Räber, Lorenz, Stähli, B.E., Rodondi, N., Stefanini, G.G.   +45 more
core   +1 more source

Influence of the Residual Gensini Score on Prognosis of Patients With ST‐Elevation Myocardial Infarction

Catheterization and Cardiovascular Interventions, Volume 108, Issue 1, Page 76-83, July 1, 2026.
ABSTRACT Background The residual Gensini score (rGS) was developed to quantify the severity of coronary atheroma burden after coronary revascularisation. The predictive value of the rGS for clinical outcomes in patients with ST‐segment elevation myocardial infarction (STEMI) remains unexplored.
Batric Popovic, Nassima Djaballah, Mirela Tomic, Renaud Fay, Victorine Fraichot, Florian Eggenspieler, Pierre Adrien Metzdorf, Jeanne Varlot, Edoardo Camenzind   +8 more
wiley   +1 more source

Safety of Prasugrel in Indian patients – Multicentric registry of 1000 cases

Indian Heart Journal, 2014
Background: Clopidogrel has been the only available antiplatelet drug used along with aspirin in patients of ACS. In recent years 2 new antiplatelet drugs (Prasugrel and Ticagrelor) have become available.
Upendra Kaul, Arvind Sethi, P. Arambam, A.K. Omar, R. Keshava, Sanjeeb Roy, Shuvanan Ray, Rakesh Jaswal, Ripan K. Gupta, Rakesh Rai Sapra, Rane Sandip Keshav, Rajpal Singh, Vineet Bhatia, Vinay Sanghi, Arun Chopra   +14 more
doaj   +1 more source

High Platelet Reactivity in Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: Randomised Controlled Trial Comparing Prasugrel and Clopidogrel.

PLoS ONE, 2015
BackgroundPrasugrel is more effective than clopidogrel in reducing platelet aggregation in acute coronary syndromes. Data available on prasugrel reloading in clopidogrel treated patients with high residual platelet reactivity (HRPR) i.e. poor responders,
Tobias Geisler, Jean Booth, Elli Tavlaki, Athanasios Karathanos, Karin Müller, Michal Droppa, Meinrad Gawaz, Monica Yanez-Lopez, Simon J Davidson, Rod H Stables, Winston Banya, Azfar Zaman, Marcus Flather, Miles Dalby, Miles Dalby   +14 more
doaj   +1 more source