Results 121 to 130 of about 37,525 (284)
Follow-up study of high-dose praziquantel therapy for cerebral sparganosis
PLoS Neglected Tropical Diseases, 2019 Background Cerebral sparganosis is the most serious complication of human sparganosis. Currently, there is no standard for the treatment of inoperable patients. Conventional-dose praziquantel therapy is the most reported treatment.
Peng Zhang +11 more
semanticscholar +1 more source
Hybridisations within the genus Schistosoma: implications for evolution, epidemiology and control [PDF]
, 2016 SUMMARYHybridization of parasites is an emerging public health concern in our changing world. Hybridization and introgression in parasites and pathogens can have major impacts on the host and the epidemiology and evolution of disease.
Leger, E, Webster, J P
core +1 more source
bioRxiv, 2019 Background Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the species of schistosome infecting humans; however, the current tablet formulation is not suitable for preschool age children mainly due to its ...
M. Mahende +7 more
semanticscholar +1 more source
The epidemiology of gonorrhoea, chlamydial infection and syphilis in four African cities.
, 2001 OBJECTIVES: To compare the epidemiology of gonorrhoea, chlamydial infection and syphilis in four cities in sub-Saharan Africa; two with a high prevalence of HIV infection (Kisumu, Kenya and Ndola, Zambia), and two with a relatively low HIV prevalence ...
Anagonou, S +11 more
core +1 more source
The cytotoxicity study of praziquantel enantiomers
Drug Design, Development and Therapy, 2016 Praziquantel (PZQ) is prescribed as a racemic mixture (racemic-PZQ, rac-PZQ), which is composed of (R)-PZQ and (S)-PZQ. In this work, the cytotoxicity of rac-PZQ and its two enantiomers (R)-PZQ and (S)-PZQ on eight cell lines (L-02, HepG2, prf-plc-5, SH-SY5Y, HUVEC, A549, HCT-15, Raw264.7) was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphe ...
Dongling Wang +5 more
openaire +4 more sources
Rare trematode infestation in irritable bowel syndrome: Pathogen or commensal?
Journal of Digestive Endoscopy, 2016 A healthy young adult male presented with complaints of frequent (>3/day) formed stools and passage of excessive mucous in stool for 3 months. He did not complain of nocturnal motions, recent diarrhea, blood in stool, straining, weight loss, or pain ...
Sunit K. Shukla +3 more
doaj +1 more source
Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules
Pharmaceuticals, 2018 Schistosomiasis is a major neglected tropical disease. Control of schistosomiasis currently relies on a single drug, praziquantel, and despite its efficacy against the all schistosome species that parasitize humans, it displays some problematic drawbacks
Maria João Gouveia +4 more
doaj +1 more source
Praziquantel Resistance in the Zoonotic Cestode Dipylidium caninum.
American Journal of Tropical Medicine and Hygiene, 2018 Dipylidium caninum is a cosmopolitan cestode infecting dogs, cats, and humans. Praziquantel is a highly effective cestocidal drug and resistance in adult cestodes has not been reported. From 2016 to 2018, a population of dogs with cestode infections that
Jeba R. J. Jesudoss Chelladurai +3 more
semanticscholar +1 more source
Differentiation of Schistosoma haematobium from related schistosomes by PCR amplifying an inter-repeat sequence. [PDF]
, 2007 Schistosoma haematobium infects nearly 150 million people, primarily in Africa, and is transmitted by select species of local bulinid snails. These snails can host other related trematode species as well, so that effective detection and monitoring of ...
Abbasi, Ibrahim +5 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2017 An efficient and alternative synthetic approach has been developed to prepare various N-(arylethyl)piperazine-2,6-diones from 4-benzenesulfonyliminodiacetic acid and primary amines using carbonyldiimidazole in the presence of a catalytic amount of DMAP ...
Ramana Sreenivasa Rao +1 more
doaj +1 more source