Results 191 to 200 of about 30,204 (224)

Praziquantel – 50 Years of Research

ChemMedChem, 2023
Investigations on praziquantel (PZQ) started fifty years ago by a cooperation between Bayer AG and Merck KGaA. Until today PZQ is the drug of choice for schistosomiasis in human medicine and used in many combinations with antinematode drugs in veterinary
A. Waechtler   +6 more
semanticscholar   +1 more source

Recent trends in praziquantel nanoformulations for helminthiasis treatment

Expert Opinion on Drug Delivery, 2022
Introduction Infections caused by parasitic flatworms impose a considerable worldwide health burden. Recently, World Health Organization launched its roadmap for neglected diseases for the period 2021 to 2030 and oral treatment with praziquantel (PZQ) in
Ana C Mengarda   +3 more
semanticscholar   +1 more source

Praziquantel

Parasitology Research, 2003
Praziquantel is the drug of choice for the treatment of all forms of schistosomiasis. This review summarizes the main features of the drug, with special attention being given to those aspects that may be of interest to the practicing physician. After a brief mention of the history, the chemistry, the major available brands and their costs, doses and ...
Donato, Cioli, Livia, Pica-Mattoccia
  +7 more sources

Theoretical Calculation and Structural Analysis of the Cocrystals of Three Flavonols with Praziquantel

, 2021
The formation of cocrystals is closely related to the weak interaction between the participant molecules.
Dezhi Yang   +7 more
semanticscholar   +1 more source

Praziquantel resistance

Expert Opinion on Drug Discovery, 2007
Results from infected patients, not cured by multiple doses of praziquantel (PZQ), have been reported from different geographic locations, suggesting that resistance to the drug may be present. This has been coupled with several in vivo (e.g., studies on mice infected with 'resistant isolates') and in vitro tests (e.g., direct application and ...
Sanaa S, Botros, James L, Bennett
openaire   +2 more sources

Glycyrrhizin-Assisted Transport of Praziquantel Anthelmintic Drug through the Lipid Membrane: An Experiment and MD Simulation.

Molecular Pharmaceutics, 2019
Praziquantel (PZQ) is one of the most widespread anthelmintic drugs. However, the frequent insufficient application of PZQ after oral administration is associated with its low solubility, penetration rate, and bioavailability.
A. V. Kim   +7 more
semanticscholar   +1 more source

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