An Overview of Pre-Analytical Factors Impacting Metabolomics Analyses of Blood Samples
MetabolitesDiscrepant sample processing remains a significant challenge within blood metabolomics research, introducing non-biological variation into the measured metabolome and biasing downstream results. Inconsistency during the pre-analytical phase can influence
Amy Thachil +4 more
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Frequencies and causes of pre-analytical errors in a tertiary care hospital laboratory in Saudi Arabia [PDF]
Annals of Saudi MedicineBACKGROUND: Errors in clinical laboratory tests can have a detrimental effect on healthcare delivery. The pre-analytical phase accounts for most laboratory errors, known as pre-analytical errors (PAEs).
Nasser Thufayl Alenezy +6 more
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Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review
Metabolites, 2019 Metabolomics provides a comprehensive assessment of numerous small molecules in biological samples. As it integrates the effects of exogenous exposures, endogenous metabolism, and genetic variation, metabolomics is well-suited for studies examining ...
Victoria L. Stevens +3 more
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Assessment of Total Laboratory Errors in Clinical Chemistry Laboratory: Experience at a Tertiary Care Hospital [PDF]
Liaquat National Journal of Primary Care, 2022 Background: Efficient Laboratory services are the backbone of the modern healthcare facility. 70% of all medical decisions are based on laboratory data.
Syeda Sabahat Haider Zaidi +2 more
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Cost of running a full-service receiving office at a centralised testing laboratory in South Africa
African Journal of Laboratory Medicine, 2022 Background: The National Health Laboratory Service operates a platform of 226 laboratories across South Africa, ranging from highly sophisticated central academic hospitals to distant rural hospitals.
Naseem Cassim +3 more
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Pre-analytical specimen labelling and processing errors in the ICU
University of Ottawa Journal of Medicine, 2022 Introduction: Specimen rejections have been associated with increased in-hospital stay and cost. The majority of errors occur in the pre-analytic phase. Specimen rejection can lead to high rate of recollection, delay in result availability, and high rate
Long Nguyen, Sherissa Microys
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Turn Around Time for Clinical Biochemistry Laboratory: A Vital and Effective Parameter for Patient Care [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Clinical laboratories are judged by its validity, reliability, genuineness or authenticity and its timeliness in reports generating.
Mitul Navinchandra Chhatriwala +3 more
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Pre-analytical rejection rates of clinical samples based on patients’ health status
Baghdad Journal of Biochemistry and Applied Biological Sciences, 2022 Background and objective: The pre-analytical rejection rate is the proportion of samples rejected at the stage that includes the initial procedures of the testing process performed outside the laboratory walls by healthcare professionals.
Adem Keskin, Recai Aci
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D-dimer Testing in Pulmonary Embolism with a Focus on Potential Pitfalls: A Narrative Review
Diagnostics, 2022 D-dimer is a multifaceted biomarker of concomitant activation of coagulation and fibrinolysis, which is routinely used for ruling out pulmonary embolism (PE) and/or deep vein thrombosis (DVT) combined with a clinical pretest probability assessment.
Loris Wauthier +13 more
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Scientific Reports, 2021 Phenylketonuria (PKU) is a genetic deficiency of phenylalanine hydroxylase (PAH) in liver resulting in blood phenylalanine (Phe) elevation and neurotoxicity.
Rachna Manek +14 more
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